Special

MmuINT0051747 @ mm9

Intron Retention

Gene
ENSMUSG00000026825 | Dnm1
Description
dynamin 1 [Source:MGI Symbol;Acc:MGI:107384]
Coordinates
chr2:32176024-32178993:-
Coord C1 exon
chr2:32178942-32178993
Coord A exon
chr2:32176138-32178941
Coord C2 exon
chr2:32176024-32176137
Length
2804 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
TCCCCCACTCCCCGTTCCAGGTC
3' ss Score
9.88
Exon sequences
Seq C1 exon
TGCTCAGCAGAGAAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAG
Seq A exon
GTGAGTGGGCCCCAGTCTCCCAGCCCAATGGATGGAGGATGCCGGAAGGACTTGGAGCTCTGAGATCCCCCTCTCCCAATGGGAAGGGTCCTACAGGGGCCAGAGAGCCTGCCCTCTGCCAGCCACAAGCTTCTCACTCTGCCTCAGTAATCTTCTTTCCTCTCTCCCCAATGATGCTTCTCCTGGTTGCTATGGTTACTTCTCCTGGTTGCTATGGTTACCTCTTTGCAGGATGAGATTCTGGTGAGTACCAGGACTGGGGGCGGGGAGGGGGTCTTGGCTTGTGCAGTGACGGGGAGTCTTGCTGGTGATGGGGATCTGCATGGGGCAGAGGGTACCCTTTGAGCACCTTACACATACCAGCACATAATTTTCACACCTGCTCACAGGACAGAGAAAGGCCCAGCCATGCTCACAGTTCCATAACCCATCTATAAATGTGCACAAGCCAAGCACCTGCTGTAGGCAGAGCTACCCTACATGGGGATGGATGGGCCCAGGGCTAGGTAGATGCTCTTTAAAAGTCTATTGGAGGAATGCTTGGTGACTGTTTGGAGTGGGTATGAGACAGGCATGTTCTTAAGAAGCAGACAGTGGAGGGCTGGAGAGATGGCTCTGTGGTTAAGTGCACCGACTGCTCTTCCAGAGGTCCTGAGTTCACTTCCCAGCAACCACATGGTGGCTCGAAACCATCTGTGAAGGGATCTAATGCCCTCTTCTGCTGTGTCTGAAGACCGCGATTGTGTACTCATATACATAAAATAAATATGTTTTTAAAGGGAGCAGACAGTGACCCCCAATGGAGAGTTAAGACATGATGAAGCCAGAAGCCCGCTCTCCTCTCCTGGCTCCTTGCCCCATGCTTCAAATGGCTGTGGAAACAGCGCTTATCAGCTTCCCTTGCCCCAATCCAGTTATGCACATGAGACCTGGAGTCTTCAGTATTTCCCACATTGTTTCCAGAGGCTGTAATTGGTGTGATAACTGTTTCCCCACCCAGCTTTGGGCCTTGGTCATCTCCCAGCCCAGGTTCTGAGTCTCGACTCACAGTAGGTGCTCAGAGAAGGAAGACCAAAAGGAATTGTATCTCAGGAAGGTTCAGAGCCTGCCCCTGCCCCATCCCTGCCTCTGCCCCATGAAGACCTGGTACCTATAGACAGGGCCCTAGTAGGGCCTCTGAGAGTCCTGGGTAGGATGAGACTCTCCAGCTCAGGTACTCCGCACGGGAGCTAGGTAGGCAGGTGAGAGAGAACATAGGCTTGGGCGTGGCTAACAGGAGGGAAAGGCTAAGTCAGCCAGGAAGCAGAGTGCACAGTGTGCAGCCAGATCATGGGACAGCAATGGACTCTGCTCCAAAGGCAGGCACTGAGGGGATCCTACTGGCAGGCTGGGAGAGAGCTGGCGAGATGTCTGGTCCCAGCCACCCTGCTAATTTGTTAATTGACCAAAGCAGCGGTGATCTCCCCTCTGCTCGGGTGCTGGTGGACTGTTGATTTCAATTCCCAGTGAGGTTCTCAGAAGCTGGATAGGGTCAGGAAAGGCTGGAAGCAAGATGTACACCCAGGCCTCCAGAGCAGCACCCATAAGGTCAGGGCCAGGGAGGGAGCAGGACACAGTCCCTCCAGTCAGGATCACAGCAGCAGGGGGCGGGGCCTGGGGAACAAGCTTGGCCTGGGGGGTGTTGTAATAGACCTCTGGACATGGACTCTTGTTACTCCCGACTTTTGATAGGAAGTTCAGGCCTGAAAAATGGGTGGCGGGCTGGAGAGATGGCTCAGCAGTTAAGAGCACTGACTGTTCTTCCAGAGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCCATAATGAGATCTGGAGTGTCTGAAGAAAGAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGGAGGGAGGGAGGGAGGGAGGGAGGGAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAAGGTGGCTTTGCTTCTCCCTTCGGCCCGAAGGCTCTTAGAACTGTAACAGCTCAGTGTTCATGTATTCATGTCACCACAAGCATCCATCCATCACTTACTGACTGACCAGCACTCTACAAAGTGATGAGGGGCACTGGGTGATGGATGCATTAACAGGAAAGGTTGTATAAGTAGGTAATATCGTTCTTTCTGGAGAGGGTGGGAGGGGGGAGAGAGAGAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAATTAAAATTGCAGTCTCTGTTACAGAAGCAAACATGAAAGACTGATCAGAGATCATTACTTGCTTCTGATTGGCGTGGGGGGCAGGGAGAGCTGCTCACCGTGTAAGTCGGAATGGATACCAGAGGGCAAGTAGGCACACACCAGGCAACAGGGAAGAGGGGCAACCGCAGCAAGTACAGGTTGCTAGGGTTAGGAACAGGCGTTTGGGACCCTCAAACGATGCTTGGAGTTCCCTTACCCTTACATCCGCCAAACTCTGCTTGCATACTGTTAGCGACGGGGAACTCACCCTCTATTAAGTGGCCAATCCCTGGTCCCTACATCTCTGGCAGATAGAAGGCACTCTATCTCGAGCTGACCTTTGCTTTCCTGTCTTCCACTCTCTTCACTTGTGGTTCAAATCAGGGCAGGTCTGGCCCCCACCCTCTCTGACCGGTCAGGCCTCAGAGAATTGGAGAAGCGGCTTTTGAAGGCCTCTTCAGTCCTCCCCTCCTCCATGGGGAAGCCGGGCCCATGCCCACCGACCTCCTCCCCCACTCCCCGTTCCAG
Seq C2 exon
GTCATTCGAAAGGGGTGGTTGACCATCAACAACATCGGCATCATGAAGGGAGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGGTACAAGGATGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026825-Dnm1:NM_010065:13
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.406 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0103115=Dynamin_M=PD(4.4=72.2)

							
A:
NA

							
C2:
PF0016924=PH=PU(35.6=97.4)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000088618





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000077461, ENSMUSP00000108977, ENSMUSP00000108979, ENSMUSP00000108981, ENSMUSP00000108992, ENSMUSP00000122679, ENSMUSP00000122679f2008A
          









    
Other Skipping Isoforms:
ENSMUSP00000039033, ENSMUSP00000118914
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr9:128239780-128239984 
ALTERNATIVE
HsaINT1011681
(DNM1)
Human
(hg19)
chr9:131002059-131004510 
HsaINT0050630
(DNM1)
Rat
(rn6)
chr3:11352646-11352871 
LOW PSI
RnoINT0049803
(Dnm1)
Cow
(bosTau6)
chr11:98862955-98865227 
ALTERNATIVE
BtaINT0051306
(DNM1)
Chicken
(galGal4)
chr17:5038788-5040007 
ALTERNATIVE
GgaINT0123839
(DNM1)
Chicken
(galGal3)
chr17:5671387-5672606 
LOW PSI
GgaINT0123839
(E1BV15_CHICK)
Zebrafish
(danRer10)
chr3:50374243-50374251 
DreINT0058787
(dnm1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"