Special

MmuINT0086548 @ mm9

Intron Retention

Gene
ENSMUSG00000036333 | Kidins220
Description
kinase D-interacting substrate 220 [Source:MGI Symbol;Acc:MGI:1924730]
Coordinates
chr12:25689918-25693075:+
Coord C1 exon
chr12:25689918-25690083
Coord A exon
chr12:25690084-25692923
Coord C2 exon
chr12:25692924-25693075
Length
2840 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
CGGCTTGGTCTTCCCCCAAGGTT
3' ss Score
6.79
Exon sequences
Seq C1 exon
TCGTCATTTACTTCGGTGGACGGCAGGAAGGAGAGAGTTGGAACTGGGCCTGGGCTCTCAGCACCAGACTGGCAAGGCACATTGGGTACCTGGAGCTCCTCTTCAAGCTGATGTTTGTGAACCCACCCGAACTACCAGAGCAAACGACAAAGGCTTTGCCTGTGAG
Seq A exon
GTGAGGTGCTCCTTTGACAGAAGGAATCTTTAATAAGGGTAACAAAAGAGTGTAAAGAATTTTACAGGTCATCATATTCCAAAAAATATTGCTACCTTAGTCTCTTAGTTGAACAAAACAAAACAAATGAAACAAAACAAAAGTATGTCCCAATACCTCTGAGAAACACTTCACAGTATATCCTCCTCCTATGCATGAGGTCGGCTTTCCACAGCATGAAATCTGCTCATTTTCATGGTATTTTATTTGTGCAGAACCCTCTCCCTCATCCTTGTACCTGTTACGTACTGAGGGCTTTTCTGGGAGCAGTGCCAGGGTTTAAACCAGGGCTCACTGAGTCACTCTCTGTGATAGGGCCACACCTCGCCTCCATTACCATCCTTTCTGATACTTTGGAAGGAGTATTGGCCTCCAGGGTAGAGCCCTGGCAGACAGAGGTCTGGAGTGAAGGCCTCGCTTCTCCTTGAAGGAACAGTAACCCCTGGAAACTCTGCTCACGCCGAGCTGCTCTCTCCTCAGCTCTGCAAGTAGACACGTGTGTCTAGAGTGATTGAGTATCTCAAACAGGAAGTCACGAGAAAGAGGTGTAATAAAGGAATAAAGAAAGGTGTAAGATTCTAGATAGAAGAAAGGGTTTTGTTTGTTTGGTTGTTTGTTTTTTAGATAGAAAATTTAGAGCAAAAAGCTTCCATAGGGGTTGGGAAGAAGAATTAAAAATCTGTTAAAGGATTATGACGTTTTAAATTATAATAAGATAAAATATGCATGAACATAAGTCATTCTAACCATCAAAGCTGTGCTAGGAATATAGGTGAGAAAAATAAAGGTTAAAAAATTACAAATACAAGCTGGAGAGATGGCTCAGTGGTTAAGACCACTGGCTGCTCTTCTAGAGGTCCTGAGTTCAATTCCTGGCAACCGCATGGTGGCTCACAACCATCTGTAATGGGATCCGATGCCCTCTCCTGACATGTACATGTAGATAGAACACTCGTATACATAAAATAAATAATAAATAAATCTTTTTTAAAAAACAAAACAACCCTTTAAAAACTTAGGAAAAAATTACAAATGTAGCTGGCTGTTTCTTACTCCTGGGTTCTATATCTCCAGATGCAACCAACTATAAATTATAAATATAAAAAAAATTGTACCTGATACCCTGCACTAAACAATACAGTGCAACCTTTGTTTACTGTTTACTGAATGTAGTGTGTTCATTGTATTAATATCATACAGAATCCAGAGATGGTTTAAAGGAGATTGCAATATGTGCACTTTTTATTTTCTATGAGAGACTTGGGCTGATCCTAGAACCAGCTACCTATGAATACTGAGGAACCATTATACTCAGCATATAAATTTAAACATTAAAAATGTAAAGCTGAGAAGTTTTAGAGGAACGTGTTTGAGGTTGGAGATGTGGCTCAGTGGTTAGAAGAGCTTGCTGCTTTTGTAGAGGACTGGTTTGCTTTTAGCACCTACAATGGGTGACTCACGACCACTTGTAACTCTACCATCAGGGCATCTGAAACCCTTGTCTGGCCTCCACGGGGATCCATACAGTGTGTGCACACACACACACACACACTATGAAGTAAATATTTTTTTAAAATAAAGCATACAATATAGGATAATACAATGGAGGGAATTTTTACAGAAAATTGAAGGTTTAAATGAACAAGATGGGCGTTTTGAAACAGAACAACCAACATGGTATCAGTCAGGACCACAATCTCTAGTCTAGTGCCATTCCAGACTGTAATCTGAAACATGTTTTATCTCCTGGGCTAAAGTGAGAATTTAGTTTAGGTATGGAAGAAAAAGAATAAATTAATGCAGAAATAAGTAATTCTGAGCCTGAAGATGTCAGAAAATCAATTTTTTGAAGAATAACTCTGAAAATAATATTTTACAATTATTTCTAAAAACCTGGTCTATGTTAAAGCTATAAATAAAATAAAACATTAAAAAAGTTTATTTATTATTTTTAGGATTTCTTTTAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTGCCTCATGTATGGCTGTGCACAGTGTATGCAGTGTATATGGAGTTCAGAGGAGGAGGTCAGATCTCTGGACTTGGAGTTGCAGACAGCTATGAACTGCCATGTAGGTGCTGGGAACTAAACCTTGGTCCTCTGGAAGAGCAGCTGGTGTAACCATTGAGCCGTCCCTCCAGCAGAAACCTTGCTTCTAAGTGATATTTCTGGGTTTGGAGTTACTGTCTGTGGTGAAGACTCTCCTGCCTGACTGCCTCAGCTGTTATTAGAGCTCTTTCTCTTTTGCCTCTGTTCTCACCCAGGCCGGGCTCTGCCATCACTCTGCCCTTTCCCGTTGGCCAGTCACACACATTGAACACGCTCGTGTCTTTGCTAAGAGAAAGTCTAACATGCTTAGCCAAGAAGATAATTAATCACACATCTGCTCCCCTCCCTTAGAACTTTAAAAGCAAGTTTTTGAAAAGAACATCAAAAAATATAGAATAAATGGGGGCTGGAGAGATGGCTCGGTGGTTAAGAGCACAGACTTCTCTTATGGGGGAATCTGGGTGGGATTCCCAGCACCCACATGGTGGTTCACAGCCATCTGTACATCCACTTCTAAGGGATTAGACGTCTTCTGTCTTCTGTGGGTACCAAGGATACATGTGGTGCATAGACTTAAAATTAAAATACTTTTTAAAAGAAGAAACAGGCACTGTCTTTAGAAAAAAGGAAATGTAGAATAACTGATAGAGATGGCATGTGTATGCTAGAAACGCTGCATTCAGTAGCTGAGTAACATCGGCTTGGTCTTCCCCCAAG
Seq C2 exon
GTTTCTGTTTACAGATTACAATAGACTCTCCAGTGTTGGGGGAGAGACTTCCTTGGCTGAAATGATCGCGACCCTCTCAGATGCTTGTGAGAGAGAATTCGGCTTTCTGGCTACCCGGCTGTTTCGAGTATTTAAGACTGAAGATTCTCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036333-Kidins220:NM_001081378:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF076939=KAP_NTPase=FE(10.7=100)

							
A:
NA

							
C2:
PF076939=KAP_NTPase=FE(12.0=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000063999





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000082672, ENSMUSP00000106558, ENSMUSP00000106560
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:8786358-8788646 
ALTERNATIVE
HsaINT0087356
(KIDINS220)
Human
(hg19)
chr2:8926488-8928776 
LOW PSI
HsaINT0087356
(KIDINS220)
Rat
(rn6)
chr6:44259293-44262276 
ALTERNATIVE
RnoINT0078758
(Kidins220)
Cow
(bosTau6)
chr11:88505584-88507240 
LOW PSI
BtaINT0081459
(KIDINS220)
Chicken
(galGal4)
chr3:95485099-95486056 
ALTERNATIVE
GgaINT0078647
(KIDINS220)
Chicken
(galGal3)
chr3:98785484-98786441 
LOW PSI
GgaINT0078647
(KIDINS220)
Zebrafish
(danRer10)
chr17:34978257-34978749 
LOW PSI
DreINT0085764
(kidins220a)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"