Special

MmuINT0103589 @ mm9

Intron Retention

Gene
ENSMUSG00000053093 | Myh7
Description
myosin, heavy polypeptide 7, cardiac muscle, beta [Source:MGI Symbol;Acc:MGI:2155600]
Coordinates
chr14:55594716-55597538:-
Coord C1 exon
chr14:55597420-55597538
Coord A exon
chr14:55594913-55597419
Coord C2 exon
chr14:55594716-55594912
Length
2507 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
3' ss Seq
TGATGCTCACCTCTTCCCAGGCC
3' ss Score
7.64
Exon sequences
Seq C1 exon
GGGAGCTGTCCCGGCAGCTGGACGAGAAGGAGGCTCTGATCTCTCAGCTAACCCGAGGCAAGCTCACATATACACAGCAGCTGGAGGACCTCAAGAGGCAACTGGAGGAGGAGGTCAAG
Seq A exon
GTAAGGCCTAGACTCTGTGTCTGGACAAAGCATAGAGTGCACCAATTGGCCAGAATATGGGTCTCTTTCTTCTCTAAGAGTGAGGCTTGTCTGGTCCACAACTTACTACAAACTGTAAAAAAGAAGTAATAACACAGCCTTTACTAAGTATCTTTTAAAATCTGTTCCCCAGGCTGAGAGAGGCCCTTTGCCCTCCTACTGCTGTGCAGGGGTGGGGAGTAGGAGGGTAAAGAGGCAGAGAGGAAATTATCTAAGATAGTGATTTTCAACCTCTGGGTTGCGACCTCTTTGGGGTCAAATAGTAGATATCATGCATGCCAGACATTTACATTCACATCTAGAACAGTAGTAAATTATAGTGTGAAGTAGCCATGACAATTTTATGGTTGAGGGTTCCTACAACGTGAGGGACTATATTAAAGGCCACAGAATTAGGCAGGCTCAGAGCCTCTGATCTGAGGAGATGGGATTTGGCCTTCTTGGGTGCAGATATTGGGTGCAGGGACTACACAGAGGGGTCCTAGGATGATGAGAGCAATCTGAAGCCTGGAAGAAGAAAGCCGGAGCCTATCCCTAGCACAGTACTGAGTTCATGGGAAAGAGATAAGGCCATGCGTTCTTAAGCCTCACAGGGCTCTGGCTGGGGAGAGAGCTCAGTCAGTAAAAGGCTTGGTGCAGGAGCATGAAGGTGTTTGGTCCTGAGTTCAGTCACCAGCACTTGTAATCTTCGCGTGGAGATGGCAGAGACAGCCATGTAGCTTGCCTGTTCTACTTTGTGGATTCTTTTTCTTCCACCCTTTCAACTCCCTAACACTAGATAAGAGAGAAAAAAGGATAGAGAAGAAAGGAAAGAGATCCCTGAATAAAGTCAGAAGTTGGAAACCGGACGATACTATTGTTAGACTATCTCTTCTCATTAGGGATGATGCTATTGTTACACTACCTCCTTCTGATTAGGGGCGTTGAGTTTGAGTTGCTTGAGGAAAGTTTGATCTTCACCACCAATATACCTAGTTGTTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCCATCTTCTTCTTCCTCTTCCTCTTCTTCCTCCTCCTCTTCCTCTTCCTCTTCTCCTTCTTTTCCCTCCTCCTCTTTCTCTCTCTCCTCCCCTTCTTCCTCCTCTTCTGTTCCCTCCTCTTCCTCCTCCTCCTCCTTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGTTTTTCGAGACAGGGTTTCTCTGTATAGCCCTGGCTGTGCTGGAACTCACTGTAGAGCAGGCTGGCCTCGAACTCAGAAATCCGCCTGCCTCTGCCTCCAAAGTGCTGGGATCAAAGGCATGTGCCACCACGCCCCGCCTCTTCCTTTCTTCTTCTCCTCCTTCTCCTCCTCCTCTTCCTCCTCCTCCTCCTTCCTCTTCTTCATCTCCTTCTCCTTCTTCTCACTCCTCCTCCTCTTTCTCTCCCTCTTTCCCTTCTTCCTCCTCTTTCTCTCTCTCTCTCTCCTCCCCTTCTTCCTCCTCCTCCTTTTCTTCTTCTGCTTCTACTCCTACCTACTCCTCCTCTTCTACTTTCTTCTTTGCACATGACTACTTAACAAACCATGAGCAACAGTGACCAACAGCAACCAATAGCAACCAACAGCAACCAACAACCCCCAAAATCCAACCCTACCTCTCTGAGTCCTAGCATTCATATACCCTCTGAAAAGTCCTTAGAATTCCAAATGTCACACAATAGCAGAAACTATCTGCAGCTGACAAGATCACACCACTGCTAGAGCACGAGGCAAATCATAGTCAGCCTCTGTGGACAATCTGAAGCAGCCCCATATCCCACTCCTGGGATTAAAACAAACACACATTCTTATAATACTTCTGTGTATTTTTTTTAAAAAAAAAAGCCAAAATTCTAAAATTATCACTACACAGGAAGATCTCTGGGACTGACTGACAGTCAGCCCAGCCAAGTTCTGAGGTCTTGGTGACAGACTTTGTCTCAGAAAAATATGGTATATGGTGTCATGTGAAAAACCCATGGTTGACTTCAGACCTCCCTACATATGTACAAACATCCCAACTCTTCCCCACAAAACCCCAAAGCTTAGTACTAACCTACCTCTTATAGTGTGGTAATCTCAAGGAAAACTTCCTGATGCCTGTTTGCACCTGTAAATGCACTGGGTGATCAGCTCTTCTGCAAGGAGCATCAGGCAGTGGACACAGAACTTTGTAAACAGTGCAGCACTGTTTTATTATTTAGGGTCATTCTTGCTCAGCAAACCACACCGGGTTCGCTGGAGAGTTGGAGGTAGATGGGGCCAAGGGATGTGTTGAGACTGGGGTAAAAGGATGGTGGAGGAAAAAGCTGACCCACTTCCTTGATGCTCACCTCTTCCCAG
Seq C2 exon
GCCAAGAACGCGCTGGCCCACGCACTGCAGTCAGCACGGCATGATTGTGACCTGCTGAGGGAACAGTATGAGGAGGAGACAGAGGCCAAGGCTGAGCTACAGCGAGTCCTGTCCAAGGCCAATTCAGAGGTGGCCCAGTGGAGGACCAAGTATGAGACGGATGCCATACAGAGGACAGAGGAGCTGGAGGAAGCCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000053093-Myh7:NM_080728:30
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.325 A=NA C2=0.394
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0003816=Filament=PD(4.2=30.0),PF0157614=Myosin_tail_1=FE(4.5=100),PF0003816=Filament=FE(12.7=100)

							
A:
NA

							
C2:
PF0157614=Myosin_tail_1=FE(7.6=100),PF0003816=Filament=FE(21.1=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000099867





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000126840
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:23418407-23419176 
LOW PSI
HsaINT0107857
(MYH7)
Human
(hg19)
chr14:23887616-23888385 
LOW PSI
HsaINT0107857
(MYH7)
Rat
(rn6)
chr15:33639905-33641855 
LOW PSI
RnoINT0096537
(Myh7)
Cow
(bosTau6)
chr10:21339295-21340276 
LOW PSI
BtaINT0097317
(MYH7)
Chicken
(galGal4)
chr18:623279-623544 
Chicken
(galGal3)
chr18:441771-442046 
ALTERNATIVE
GgaINT0127797
([1])
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"