MmuINT0104564 @ mm9
Intron Retention
Gene
ENSMUSG00000030761 | Myo7a
Description
myosin VIIA [Source:MGI Symbol;Acc:MGI:104510]
Coordinates
chr7:105217882-105219639:-
Coord C1 exon
chr7:105219412-105219639
Coord A exon
chr7:105218053-105219411
Coord C2 exon
chr7:105217882-105218052
Length
1359 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
ACGGTGTGTGTCACCCTCAGGAG
3' ss Score
8.81
Exon sequences
Seq C1 exon
GTGTCCTCCCTGGGCAGCGGCAGTGACCATGTCATGGATGCCATCTCTCAGTGTGAGCAGTACGCCAAGGAGCAGGGTGCTCAGGAGCGCAACGCCCCATGGAGGCTCTTCTTTAGAAAGGAGGTCTTCACACCCTGGCACAACCCCTCGGAGGACAACGTGGCCACGAACCTCATCTACCAGCAGGTGGTGCGAGGAGTCAAGTTTGGGGAGTACAGGTGTGAGAAG
Seq A exon
GTAAGTGGGGTGTGCAAGCCACAGGGAGGCCATGGCCACAGGCTAAGGGCTGTTGTCAGTTGGCTGGCGGTTGGACACTTTCTGGGTTTCTTGTGGATTCAGTGCTTCTTAACCTCACACAAGCTGTGTGCAGTGGATGCTCAGAAAGCTATCCTGATTCCCCATGAGAAGGGGTTCATGCACTCTGCAGTGCACTGCGTGATACCAGTAGGGGTGATGGACATGTTTGTATGGTTCTTAGTCTAGGAACTGCTCTGAAGGAGAAGATCAGGATTTGCAGGGTCTGCATGCTATGAGCCGAGCCGGCTCAGAGCCTGTCCCTGGGATCAGCCTTCCAGGGGACCTAGGACACACACACTCTTCTGGGCCTCGGGGCTATCTGTGCTCATGCAGTTGTCACAGTGGGTGACCCTTTGAAGTCCTTCTCTGACCCTGTCTTTCCTCCCACGGGAACAGACTCGAGGGTCTTGTTTTTGAAGATAGTGGTGGTGCTTCCTGTACCTGTGGCTCTGTTAGTGATGGCAGGATAAAGATCGATGTGCTGTTGATTTTGAGGATGGTTGTTGTTGGTGATGATGGTGGTCCTGATGCTGCTGCTGATATTCATAGGTGTTGGTAGTGAAGGTGACATTAGTGATACTGGTAGTGCTGATAGTGATGATGTATATGCTGATAAGCTAATATTCCAACTGTTTTAGAGCCACCATACTGGCTACTAAAATTGGGAAACTTTTCCCACCAACTATAAAATAGCAGATGCTTACAAGGTCCCTGAGAGCCTCCTCTGTCACACTGCTGCTCTACAGAAACACCAAGAGCCCCAGGGGAGTTCTGCCCTGCATGCTGGGCACCAGGCCTCATCCAAGAAGAGCCCAGCCCATGCCAGACTCTCACCTGGCTCTCTGAAGTAGAGCCAGGTGGTTACCATGTCGACTCTTCCTGGGTAGATAGTGATGGGGATGGGGATGTTGACAGTGGTGTGTTGACACCATCCCCACAGACCATCTCCAGTGTCCCACCCTCCAAGACATGACTGCCAGCCCACGTGGCTTTCATGCAACACCGATCCCAGCTGTCTGACCATCACCAAATAGGCCTCCTGCTCTTTTGCTCAGTTTATGTGGCCCTGGACAGAAGTCAGCTCTGAGCTGGTGCCAAGGGGACCAGACACGGGGCAAGAAGAGTATGGCTATGGGCTTAGGGACCCCATGATTGCCTTGTGAAGAGAAGTGAGACAGGGAGAACACAGAGTCCTGAGGGTCAGGGTCCCCAAACTACAGGAGACATGATTGGGAGGGGGCTGGGCTAGAAGGGCATCCCCTAGGGATGATTGGTGATGACGGTGTGTGTCACCCTCAG
Seq C2 exon
GAGGACGACCTGGCTGAGCTGGCTTCTCAGCAGTACTTTGTGGACTATGGTTCTGAGATGATTCTGGAGCGCCTGCTGAGCCTCGTGCCCACTTACATCCCTGACCGTGAGATCACACCGCTGAAGAATCTTGAGAAGTGGGCACAGCTGGCCATTGCTGCCCACAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030761-Myo7a:NM_008663:31
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF093795=FERM_N=PD(47.3=56.6),PF0037313=FERM_M=PU(32.6=38.2)
A:
NA
C2:
PF0037313=FERM_M=FE(62.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGCCATCTCTCAGTGTGAGC
R:
CAGCTGTGCCCACTTCTCAAG
Band lengths:
342-1701
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: