MmuINT0139614 @ mm10
Intron Retention
Gene
ENSMUSG00000064329 | Scn1a
Description
sodium channel, voltage-gated, type I, alpha [Source:MGI Symbol;Acc:MGI:98246]
Coordinates
chr2:66320868-66322492:-
Coord C1 exon
chr2:66322254-66322492
Coord A exon
chr2:66321042-66322253
Coord C2 exon
chr2:66320868-66321041
Length
1212 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAGT
5' ss Score
10.47
3' ss Seq
TAATATGGTTTTGCTTTTAGGTC
3' ss Score
9.81
Exon sequences
Seq C1 exon
AACTAGAAGAATCCAGGCAGAAATGTCCACCCTGTTGGTATAAATTTTCCAACATATTCTTAATTTGGGACTGTTCTCCATATTGGCTGAAAGTTAAACATATTGTCAACCTGGTGGTGATGGACCCATTTGTTGATCTGGCCATTACCATCTGCATTGTGTTAAATACGCTCTTCATGGCTATGGAGCACTACCCCATGACTGAACATTTCAACCATGTTCTTACAGTGGGAAACTTG
Seq A exon
GTAAGTGTGCAAGAAGGTAAATAAATGAGCTTGGTCTTCAAATTTTCTGCTTAAGAAACTGTTTATTATCTTCAATAGTTTATTAGACCTCTTTCAACCACAATTCCTGCATCCCTAAGGCAATAATATCCAGACGGGTACACACTACCTTTTGCCAAATAATGGCCTTTAATGTCTGTGCAAAAACTGAGAAATAGAACATAGACCTGTAATAATAATTTAAAAAGTCAGTAATGGTGTTCTTTCAGAATCTAAGGCCATGTTCTTCTTTAAATGATAAGATCACTCTGTCCTAGCTCCAGATGGTTCAAATAAGGTCATGAGTTCTCTTCCTTATATGCTCTTTCAAAGAATGATAACACAAAAGTGTCTCCATCTTTTTTCCTTCCAGGGTCAAGGGAGTCTAAGTTCTGTTCTAGATTCATATCATGAAATATTGACAGTACCTAGTGCATTTTGTACATCATATGATTAGTAAGCCCATTTTTAGTGAAAGTTTCGACAATATTCTCCATTTTTTACTTTGAAGCATAAATTGTTAAAATATTTTCCAGCAGACTCAACTTAAAAGTCTCAGGTTTTTATTTGAAGAAAGAACTATCTAAAGTATAACATGCATTCTATATAATATCTAGGAGAATGTTTAGTATCTTGCTGATAAAGACAATGTAAATATGCATATGCTATAGTGGATTTATATTTTTAAATCTCTACTATTTAGATTCTGGAAACGCACTTTTAGTGCATGTGACTAATATTAATGATAGTGATGAGAATAATATAAGATACACATGATTTGAAGGGAATAAAGATAAACTTACAAATAAAATGTTTTGGGGCAAAATCTTGTCTAGGTGACATGAGGTCTGGAAGTTGGTTAATAATAGATGGGCATTTTATATACCTTGAAATATTGTTCTCTTCATCTGTAATAAAATAGTTACAGCATTTACACTATCTGGTTATTGGAGCTTCTATGAGCATAAAACAGTAAACTAATATAAACCAGCATTGTCAAATAAACTTGTAGGATAATCTTAGGATCAATAATGGAAAAGTAGAAGTAGCATTAGTCTTTTATATATATATATATATATATATATATATATATATATATATATATATATATATGTATATACATATATATATATAATATTATCTTTGATGTTATCACTATCTAAGATAATTTAAATAATATGGTTTTGCTTTTAG
Seq C2 exon
GTCTTCACTGGGATTTTCACAGCAGAAATGTTCCTGAAAATCATCGCAATGGATCCTTACTATTACTTCCAAGAAGGCTGGAATATCTTTGATGGTTTCATTGTGACACTCAGCCTGGTAGAACTTGGCCTTGCCAATGTGGAAGGATTGTCAGTTCTCCGTTCATTTCGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000064329:ENSMUST00000112366:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PU(1.6=3.8)
A:
NA
C2:
PF0052026=Ion_trans=FE(30.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCAGAAATGTCCACCCTGTT
R:
CAAGGCCAAGTTCTACCAGGC
Band lengths:
357-1569
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types