RnoEX6016665 @ rn6
Exon Skipping
Gene
ENSRNOG00000010897 | Nek6
Description
NIMA-related kinase 6 [Source:RGD Symbol;Acc:727779]
Coordinates
chr3:22871942-22884856:+
Coord C1 exon
chr3:22871942-22872049
Coord A exon
chr3:22879698-22879792
Coord C2 exon
chr3:22884743-22884856
Length
95 bp
Sequences
Splice sites
3' ss Seq
CACCCCTTGCTGTGTTGCAGTGG
3' ss Score
7.57
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
ACATCAAGCCTGCCAACGTGTTCATCACAGCTACGGGCATCGTGAAGCTTGGTGACCTCGGCCTGGGCCGCTTCTTCAGCTCAGAGACCACTGCAGCCCACTCGCTAG
Seq A exon
TGGGAACACCATACTATATGTCACCCGAGAGGATCCACGAGAATGGCTACAACTTCAAGTCAGACATCTGGTCCCTAGGCTGCCTGCTGTATGAG
Seq C2 exon
ATGGCAGCTCTTCAGAGCCCCTTCTATGGAGATAAGATGAATCTCTTCTCCCTCTGCCAGAAGATTGAGCAGTGTGACTACCCGCCTCTCCCGGGGGAGCACTACTCTGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010897-'18-12,'18-11,21-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(13.8=100)
A:
PF0006920=Pkinase=FE(11.9=100)
C2:
PF0006920=Pkinase=FE(14.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGCCAACGTGTTCATCACA
R:
GCTCAATCTTCTGGCAGAGGG
Band lengths:
170-265
Functional annotations
There are 1 annotated functions for this event
PMID: 16476580
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, pull down. ELM ID: ELMI002027; ELM sequence: YYMSPE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]