MmuEX6100956 @ mm9
Exon Skipping
Gene
ENSMUSG00000026749 | Nek6
Description
NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638]
Coordinates
chr2:38425148-38438016:+
Coord C1 exon
chr2:38425148-38425255
Coord A exon
chr2:38432759-38432853
Coord C2 exon
chr2:38437903-38438016
Length
95 bp
Sequences
Splice sites
3' ss Seq
CACCCCTTGCTGTGTTGCAGTGG
3' ss Score
7.57
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
ACATCAAGCCCGCCAACGTGTTCATCACAGCTACGGGCATTGTGAAGCTTGGTGACCTCGGCCTGGGCCGCTTCTTCAGCTCGGAGACCACTGCGGCCCACTCACTAG
Seq A exon
TGGGAACACCATACTACATGTCACCCGAGAGAATCCATGAGAATGGCTACAACTTCAAGTCAGACATCTGGTCCCTAGGCTGCCTGCTGTATGAG
Seq C2 exon
ATGGCAGCTCTCCAGAGCCCCTTCTATGGAGATAAGATGAATCTCTTCTCCCTCTGCCAAAAGATTGAGCAGTGTGACTACCCGCCTCTCCCGGGAGAGCACTACTCTGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026749-'16-18,'16-16,19-18=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(13.8=100)
A:
PF0006920=Pkinase=FE(11.9=100)
C2:
PF0006920=Pkinase=FE(14.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCACAGCTACGGGCATTGTG
R:
CGGGTAGTCACACTGCTCAAT
Band lengths:
169-264
Functional annotations
There are 1 annotated functions for this event
PMID: 16476580
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, pull down. ELM ID: ELMI002027; ELM sequence: YYMSPE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: