Special

FBgn0000036 @ dm6

Biotype
protein_coding
Gene Symbol
nAChRalpha1
Description
The gene nicotinic Acetylcholine Receptor alpha1 is referred to in FlyBase by the symbol Dmel AChRalpha1 (CG5610, FBgn0000036). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:24393896..24457157. Its molecular function is described by: neurotransmitter receptor activity; acetylcholine-gated cation-selective channel activity; acetylcholine receptor activity. It is involved in the biological process described with 8 unique terms, many of which group under: cellular process; cell communication; signaling; biological regulation; synaptic signaling. 26 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; chemical resistant; some die during pupal stage; memory defective; fertile; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 12-24 hour embryonic stages, during early larval stages.
Coordinates
chr3R:24393896-24457157:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
38
chr3R:24435073-24435110
-
5.57
23.77
0
Intron Retention
75
chr3R:24404894-24404968
-
3.42
27.15
0
Intron Retention
1171
chr3R:24403511-24404681
-
7.77
52.78
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000101204 CHRNA4 5-to-9
Human hg38 ENSG00000117971 CHRNB4 5-to-9
Human hg38 ENSG00000120903 CHRNA2 5-to-9
Human hg38 ENSG00000138435 CHRNA1 5-to-9
Human hg38 ENSG00000147434 CHRNA6 5-to-9
Human hg19 ENSG00000101204 CHRNA4 5-to-9
Human hg19 ENSG00000117971 CHRNB4 5-to-9
Human hg19 ENSG00000120903 CHRNA2 5-to-9
Human hg19 ENSG00000138435 CHRNA1 5-to-9
Human hg19 ENSG00000147434 CHRNA6 5-to-9
Mouse mm10 ENSMUSG00000022041 Chrna2 5-to-9
Mouse mm10 ENSMUSG00000027950 Chrnb2 5-to-9
Mouse mm10 ENSMUSG00000031492 Chrnb3 5-to-9
Mouse mm10 ENSMUSG00000032303 Chrna3 5-to-9
Mouse mm10 ENSMUSG00000035200 Chrnb4 5-to-9
Mouse mm9 ENSMUSG00000022041 Chrna2 5-to-9
Mouse mm9 ENSMUSG00000027950 Chrnb2 5-to-9
Mouse mm9 ENSMUSG00000031492 Chrnb3 5-to-9
Mouse mm9 ENSMUSG00000032303 Chrna3 5-to-9
Mouse mm9 ENSMUSG00000035200 Chrnb4 5-to-9
Rat rn6 ENSRNOG00000012283 Chrna6 5-to-9
Rat rn6 ENSRNOG00000013829 Chrna3 5-to-9
Rat rn6 ENSRNOG00000017424 Chrna2 5-to-9
Rat rn6 ENSRNOG00000018286 Chrna1 5-to-9
Rat rn6 ENSRNOG00000020778 Chrnb2 5-to-9
Cow bosTau6 ENSBTAG00000002252 CHRNA2 5-to-9
Cow bosTau6 ENSBTAG00000013657 CHRNA5 5-to-9
Cow bosTau6 ENSBTAG00000014050 CHRNB3 5-to-9
Cow bosTau6 ENSBTAG00000014056 CHRNA6 5-to-9
Cow bosTau6 ENSBTAG00000018253 CHRNA1 5-to-9
Chicken galGal4 ENSGALG00000003005 CHRNB4 5-to-9
Chicken galGal4 ENSGALG00000003021 CHRNA5 5-to-9
Chicken galGal4 ENSGALG00000005801 CHRNA4 5-to-9
Chicken galGal4 ENSGALG00000015384 CHRNB3 5-to-9
Chicken galGal4 ENSGALG00000016565 CHRNA2 5-to-9
Chicken galGal3 ENSGALG00000003005 F1NWX4_CHICK 5-to-9
Chicken galGal3 ENSGALG00000003021 F1NIT6_CHICK 5-to-9
Chicken galGal3 ENSGALG00000005801 ACHA4_CHICK 5-to-9
Chicken galGal3 ENSGALG00000015384 F1NA49_CHICK 5-to-9
Chicken galGal3 ENSGALG00000016565 F1N9F1_CHICK 5-to-9
Zebrafish danRer10 ENSDARG00000003420 chrna5 5-to-14
Zebrafish danRer10 ENSDARG00000006602 chrna2a 5-to-14
Zebrafish danRer10 ENSDARG00000038508 chrnb3b 5-to-14
Zebrafish danRer10 ENSDARG00000052764 chrnb3a 5-to-14
Zebrafish danRer10 ENSDARG00000057025 chrna2b 5-to-14