Special

FBgn0259228 @ dm6

Biotype
protein_coding
Gene Symbol
C3G
Description
The gene C3G guanyl-nucleotide exchange factor is referred to in FlyBase by the symbol DmelC3G (CG42328, FBgn0259228). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is X:6780790..6803593. Its molecular function is described by: Ras guanyl-nucleotide exchange factor activity; Rap guanyl-nucleotide exchange factor activity. It is involved in the biological process described with 7 unique terms, many of which group under: regulation of GTPase activity; developmental process; regulation of catalytic activity; regulation of molecular function; biological regulation. 19 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; wing vein L3; longitudinal muscle; hemocyte; imaginal tissue. The phenotypic classes of alleles include: partially lethal; phenotype; increased mortality; short lived. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages.
Coordinates
chrX:6780790-6803593:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
24
chrX:6785511-6785534
-
5.78
57.75
0
Exon Skipping
153
chrX:6787096-6787248
-
76.94
76
0
Exon Skipping
1450
chrX:6789712-6791161
-
10.01
60.42
0
Intron Retention
538
chrX:6786813-6787350
-
45.53
81.21
0
Intron Retention
1420
chrX:6784736-6786155
-
7.72
85
0
Intron Retention
111
chrX:6783779-6783889
-
28.55
100
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000107263 RAPGEF1 1-to-1
Human hg19 ENSG00000107263 RAPGEF1 1-to-1
Mouse mm10 ENSMUSG00000039844 Rapgef1 1-to-1
Mouse mm9 ENSMUSG00000039844 Rapgef1 1-to-1
Rat rn6 ENSRNOG00000014316 Rapgef1 1-to-1
Cow bosTau6 ENSBTAG00000020791 RAPGEF1 1-to-1
Chicken galGal4 ENSGALG00000003712 RAPGEF1 1-to-2
Chicken galGal3 ENSGALG00000003712 RAPGEF1 1-to-2
Zebrafish danRer10 ENSDARG00000015971 rapgef1b 1-to-2
Zebrafish danRer10 ENSDARG00000043593 rapgef1a 1-to-2