BtaEX6009416 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000038180 | SCN2A
Description
sodium channel, voltage gated, type II alpha subunit [Source:HGNC Symbol;Acc:HGNC:10588]
Coordinates
chr2:31002518-31017348:-
Coord C1 exon
chr2:31016869-31017348
Coord A exon
chr2:31006613-31006733
Coord C2 exon
chr2:31002518-31002672
Length
121 bp
Sequences
Splice sites
3' ss Seq
TTTGTGGAATTGATTTTCAGAAG
3' ss Score
4.57
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GTTCTGAACCTCTTCCTAGCCTTACTCTTGAGTTCATTCAGTTCTGACAATCTTGCCGCCACTGATGATGATAATGAAATGAATAATCTCCAGATTGCTGTGGGAAGGATGCAAAAAGGAATCGATTTTGTTAAAAGAAAAATACGTGAATTTATTCAGAAAGCCTTTGTTAGAAAGCAGAAAGCTTTAGATGAAATTAAACCTCTGGAAGATCTAAATAACAAAAAAGACAGCTGTATTTCCAACCATACCACGATAGAAATAGGCAAAGACCTCAATTATCTCAAAGATGGCAATGGAACTACCAGTGGCATCGGCAGCAGTGTAGAAAAGTATGTCGTGGATGAAAGTGATTACATGTCCTTCATAAACAACCCCAGCCTCACTGTGACTGTACCAATTGCTGTCGGAGAGTCTGACTTTGAAAATTTAAATACTGAAGAATTCAGCAGCGAGTCAGATATGGAAGAAAGCAAAGAG
Seq A exon
AAGCTAAATGCAACTAGTTCATCTGAAGGCAGCACAGTTGATATAGGAGCTCCCGCTGAGGGGGAACAACCTGAAGCTGAGCCTGAAGAATCTCTGGAGCCTGAAGCCTGTTTTACGGAAG
Seq C2 exon
ACTGTGTGCGGAAGTTTAAGTGTTGTCAGATAAGCATAGAAGAAGGCAAAGGGAAACTCTGGTGGAACTTGAGAAAAACTTGCTATAAGATAGTGGAGCATAACTGGTTTGAAACCTTCATTGTCTTCATGATTCTGGTCAGCAGTGGGGCACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000038180-'21-20,'21-19,22-20=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.119 A=0.780 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.0),PF065128=Na_trans_assoc=PU(61.3=85.0)
A:
PF065128=Na_trans_assoc=FE(18.0=100)
C2:
PF065128=Na_trans_assoc=PD(19.8=84.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCTCACTGTGACTGTACCA
R:
CCCACTGCTGACCAGAATCAT
Band lengths:
251-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]