MmuEX1023102 @ mm10
Exon Skipping
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65717388-65728540:+
Coord C1 exon
chr2:65717388-65717867
Coord A exon
chr2:65726328-65726448
Coord C2 exon
chr2:65728386-65728540
Length
121 bp
Sequences
Splice sites
3' ss Seq
TCTGTGGGGTTGGTTTTCAGAAA
3' ss Score
7.23
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
Exon sequences
Seq C1 exon
GTTCTGAACCTCTTCTTGGCCTTGCTCCTCAGTTCTTTCAGCTCGGACAACCTGGCTGCCACAGATGACGATAACGAAATGAACAACCTCCAGATAGCCGTGGGAAGGATGCAGAAGGGGATTGATTTTGTTAAAAGGAAGATACGTGAATTCATTCAGAAAGCCTTTGTCAGAAAGCAGAAAGCTCTAGATGAAATCAAACCCCTTGAAGATCTGAATAACAAGAAAGACAGTTGTATCTCCAACCACACAACCATAGAAATAGGCAAGGACCTGAATTACCTCAAAGATGGAAACGGGACGACCAGTGGCATAGGCAGCAGTGTGGAGAAGTACGTGGTAGATGAGAGTGATTACATGTCATTCATCAACAACCCCAGCCTCACCGTGACTGTGCCCATTGCTGTGGGAGAGTCTGACTTTGAAAACTTAAATACAGAAGAATTCAGCAGTGAATCAGATATGGAAGAAAGCAAGGAG
Seq A exon
AAATTGAATGCAACTAGTTCATCTGAAGGCAGTACAGTTGATATAGGTGCTCCTGCAGAGGGAGAGCAACCAGAGGCCGAACCAGAAGAGTCCCTTGAGCCAGAAGCCTGTTTCACAGAAG
Seq C2 exon
ACTGTGTAAGAAAGTTCAAGTGTTGTCAGATAAGCATAGAAGAAGGCAAAGGCAAACTCTGGTGGAACTTGAGGAAAACCTGCTACAAGATAGTAGAGCACAACTGGTTTGAAACCTTCATCGTCTTCATGATTCTGCTCAGCAGCGGTGCTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318-'29-32,'29-31,34-32
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.146 A=0.780 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.0),PF065128=Na_trans_assoc=PU(61.3=85.0)
A:
PF065128=Na_trans_assoc=FE(18.0=100)
C2:
PF065128=Na_trans_assoc=PD(19.8=84.6)
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATAGGCAGCAGTGTGGAG
R:
TCAAGTTCCACCAGAGTTTGCC
Band lengths:
242-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types