RnoEX6017129 @ rn6
Exon Skipping
Gene
ENSRNOG00000005018 | Scn2a
Description
sodium voltage-gated channel alpha subunit 2 [Source:RGD Symbol;Acc:3632]
Coordinates
chr3:51789816-51801042:+
Coord C1 exon
chr3:51789816-51790295
Coord A exon
chr3:51798813-51798933
Coord C2 exon
chr3:51800888-51801042
Length
121 bp
Sequences
Splice sites
3' ss Seq
TCTGTGGGGTTGGTTTTCAGAAA
3' ss Score
7.23
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
GTCCTGAACCTCTTCTTGGCCTTGCTCCTCAGTTCTTTCAGCTCAGACAACCTGGCTGCCACAGATGACGATAACGAAATGAACAACCTCCAGATAGCCGTGGGAAGGATGCAGAAGGGAATTGATTTTGTTAAAAGGAAGATACGTGAATTCATTCAGAAAGCCTTTGTCAGAAAGCAGAAAGCTTTAGATGAAATCAAACCGCTGGAAGATCTGAATAACAAGAAAGACAGTTGTATCTCCAACCACACGACCATAGAAATAGGCAAGGACCTCAATTACCTCAAAGATGGAAACGGGACGACCAGTGGCATAGGCAGCAGTGTGGAGAAGTATGTGGTAGATGAGAGTGATTACATGTCGTTCATAAACAACCCCAGCCTCACCGTGACTGTGCCCATCGCCCTTGGAGAGTCTGACTTTGAAAACTTAAACACGGAAGAATTCAGTAGTGAGTCAGATATGGAAGAAAGCAAGGAG
Seq A exon
AAATTGAATGCAACTAGCTCATCTGAGGGCAGTACGGTTGATATAGGCGCTCCGGCAGAGGGAGAGCAGCCAGAGGCCGAACCGGAAGAATCGCTTGAACCGGAAGCGTGTTTCACAGAAG
Seq C2 exon
ACTGTGTGAGAAAGTTCAAGTGTTGTCAGATAAGCATAGAAGAGGGCAAAGGCAAGCTCTGGTGGAACTTGAGGAAAACGTGCTACAAGATAGTAGAGCATAACTGGTTTGAAACCTTCATCGTCTTTATGATTCTGCTCAGCAGTGGTGCTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000005018-'25-31,'25-30,27-31=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.115 A=0.780 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.0),PF065128=Na_trans_assoc=PU(61.3=85.0)
A:
PF065128=Na_trans_assoc=FE(18.0=100)
C2:
PF065128=Na_trans_assoc=PD(19.8=84.6)
Main Skipping Isoform:
ENSRNOT00000007069fB12982
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAGGCAGCAGTGTGGAGAAGT
R:
TCCTCAAGTTCCACCAGAGCT
Band lengths:
242-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]