Special

DmeEX0000840 @ dm6

Exon Skipping

Gene
FBgn0033368 | CG13743
Description
This gene is referred to in FlyBase by the symbol DmelCG13743 (FBgn0033368). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:9044850..9060608. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:9047914-9050132:-
Coord C1 exon
chr2R:9049880-9050132
Coord A exon
chr2R:9048176-9048337
Coord C2 exon
chr2R:9047914-9048026
Length
162 bp
Sequences
Splice sites
3' ss Seq
TTGGACATCCGTCCGTGCAGCTT
3' ss Score
5.36
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
CCATGATTTCCTACAACGTGGTGGTGGGCGATACGCTGTCGAAGGTTCTGGTCCGCTTCTTCCCCTCCTGGGGCGGTTCCATGGGCGCCGTCCGACTGGGCGTGGTCTTCTTCGTCAACGTGGGCGTGGTGATGCCCCTCTGTCTCTACAAGAACGTCTCCAGACTGGCCAGAGCCAGCTTCATTAGCCTGGCGTGCGTGGTCTTCATCCTGTTTGCCGTCATCATCAAGCTCATGTCGGGCGATTATAAGGT
Seq A exon
CTTTCATGTGTCATCACAACACCTTCCTCGTTTATCAATCGATGCGCGACGCGACCATGGAGCGCTGGGAGAAGGTCACCCACATTTCGATTGGATTTGCCTGGACGGTGGCGGCCCTCTTCGGCATCGCCGGCTACTCCACCTTCCGCGCTCTTTCCCAAG
Seq C2 exon
GCGACCTGCTGGAGAACTACTGCTGGGATGACGACCTGATGAACTTCTCGCGTGTGCTCTTCTCCATATCGATACTCCTGACCTTCCCCATCGAGTGCTTCGTGTCCCGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033368_MULTIEX1-2/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0149013=Aa_trans=FE(20.6=100)
A:
PF0149013=Aa_trans=FE(13.2=100)
C2:
PF0149013=Aa_trans=PD(2.2=36.4)


Main Inclusion Isoform:
FBpp0087743


Main Skipping Isoform:
FBpp0308396


Other Inclusion Isoforms:
FBpp0300980


Other Skipping Isoforms:
NA
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGGTCTTCTTCGTCAACGT
R:
TGGGGAAGGTCAGGAGTATCG
Band lengths:
243-405
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)