Special

DmeEX0007147 @ dm6

Exon Skipping

Gene
FBgn0028646 | aralar1
Description
The gene aralar1 is referred to in FlyBase by the symbol Dmelaralar1 (CG2139, FBgn0028646). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 3R:30445635..30455867. Its molecular function is described by: L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; transmembrane transporter activity; identical protein binding; calcium ion binding. It is involved in the biological process described with 6 unique terms, many of which group under: transport; ion transmembrane transport; dicarboxylic acid transport; amino acid transport; localization. 17 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages.
Coordinates
chr3R:30448896-30449959:-
Coord C1 exon
chr3R:30449807-30449959
Coord A exon
chr3R:30449046-30449208
Coord C2 exon
chr3R:30448896-30448987
Length
163 bp
Sequences
Splice sites
3' ss Seq
CAACATTATATTTCGAATAGGAA
3' ss Score
4.77
5' ss Seq
ATGGTGAGA
5' ss Score
7.23
Exon sequences
Seq C1 exon
TCTCCGTCGCTTTTGAAGCGCGCCGGCACCGAAAAGTTGCGAGAGGTGTTCCTGAAGTACGCATCCATCCAGAAGAATGGCGAGCACTATATGACCAGCGAGGACTTCGTGCGAAAGTTCCTGGGACTCTTTTCCGAATCTGCATTTAATGAC
Seq A exon
GAATCGGTGCGCCTGCTGGCCAACATTGCGGACACGAGCAAGGATGGACTCATCTCCTTCTCGGAGTTCCAGGCGTTCGAGGGTCTGCTCTGCACTCCAGATGCCCTCTACAGGACCGCTTTCCAGCTGTTCGACCGCAAGGGCAACGGCACTGTTTCCTATG
Seq C2 exon
CTGACTTCGCTGATGTCGTACAAAAAACTGAACTGCACTCAAAGATACCTTTTAGCTTAGATGGCCCCTTTATCAAGCGCTACTTTGGTGAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0028646-'4-7,'4-6,7-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.007 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF138331=EF-hand_8=PU(47.1=47.1)
A:
PF138331=EF-hand_8=PD(49.0=45.5),PF134991=EF-hand_7=PU(19.6=34.5)
C2:
PF134991=EF-hand_7=FE(30.9=100)


Main Inclusion Isoform:
FBpp0297541


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0085054, FBpp0085055, FBpp0085056, FBpp0085057, FBpp0303322


Other Skipping Isoforms:
NA
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
ACCGAAAAGTTGCGAGAGGTG
R:
ATCACCAAAGTAGCGCTTGAT
Band lengths:
218-381
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)