DmeEX6002805 @ dm6
Exon Skipping
Gene
FBgn0086448 | Gpi1
Description
The gene Phosphatidylinositol glycan anchor biosynthesis class Q is referred to in FlyBase by the symbol DmelPIG-Q (CG32578, FBgn0086448). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:16359143..16361275. Its molecular function is described by: phosphatidylinositol N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process. 15 alleles are reported. The phenotype of these alleles manifest in: polytene chromosome. The phenotypic classes of alleles include: some die during larval stage; lethal; wild-type; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages.
Coordinates
chrX:16360050-16360564:+
Coord C1 exon
chrX:16360050-16360158
Coord A exon
chrX:16360223-16360358
Coord C2 exon
chrX:16360420-16360564
Length
136 bp
Sequences
Splice sites
3' ss Seq
TTATTGCTTATCTATTGTAGTAC
3' ss Score
5.85
5' ss Seq
TGGGTAAGC
5' ss Score
8.84
Exon sequences
Seq C1 exon
ATCTCGACCGGCTAATATAGTTCTTGATAGAATACTGGGGATTATATTGATGCTAATACTATTTACGCTTGCCACACAGCCTGGTGATTTTCTAATACAAATATCTCAT
Seq A exon
TACGTTATTGACGAATTGTACGGCCTGTTGAAAGTATTAGAGGGCAGTCCCATTGGCCTCAAGCTAAATATACATTTAAATAATTTCTTTCTCGACTGCTTCAAATATCATATTGAGCTGTGGTCAACATTTTTGG
Seq C2 exon
ATTTCATTGAACCTTTAGTACGACAAGTTTTCTTGGCCATTGGAATGATTGGATGCTTGGGTTTTACATTCCAGATAGCCTTACTAGTGGACTTAATATCCGTTATTGGCTTACATTCACATTGCTTCTATATTTATACCAAAGT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0086448-'1-4,'1-3,2-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0502410=Gpi1=FE(19.1=100)
A:
PF0502410=Gpi1=FE(23.9=100)
C2:
PF0502410=Gpi1=FE(25.5=100)
Main Inclusion Isoform:
FBpp0298004
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0309273
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
ATCTCGACCGGCTAATATAGTTCT
R:
ATATAGAAGCAATGTGAATGTAAGCC
Band lengths:
242-378
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)