DmeEX6007066 @ dm6
Exon Skipping
Gene
FBgn0015791 | Rab14
Description
The gene Rab14 is referred to in FlyBase by the symbol DmelRab14 (CG4212, FBgn0015791). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:14355145..14358764. Its molecular function is described by: GTP binding; GTPase activity. It is involved in the biological process described with 9 unique terms, many of which group under: intracellular transport; response to external stimulus; inorganic ion homeostasis; cell communication; peptide transport. 15 alleles are reported. The phenotypes of these alleles manifest in: phagocytic vesicle; hemocyte. The phenotypic classes of alleles include: fertile; wild-type; flight defective; immune response defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages.
Coordinates
chr2L:14357341-14357937:+
Coord C1 exon
chr2L:14357341-14357454
Coord A exon
chr2L:14357520-14357700
Coord C2 exon
chr2L:14357755-14357937
Length
181 bp
Sequences
Splice sites
3' ss Seq
CTCTACTTGCCGTCCTGCAGTCA
3' ss Score
6.86
5' ss Seq
GCGGTAAGC
5' ss Score
8.99
Exon sequences
Seq C1 exon
GTCCCAACATGACTGCAGCGCCATACAACTACAACTATATCTTTAAATACATCATCATTGGTGACATGGGCGTGGGCAAGTCCTGCCTGCTCCACCAGTTCACCGAGAAGAAAT
Seq A exon
TCATGGCCAATTGTCCTCACACCATTGGCGTGGAGTTCGGCACACGCATCATTGAGGTGGACGACAAAAAGATCAAGCTACAGATCTGGGACACAGCGGGTCAGGAGCGATTCAGGGCAGTGACACGCTCCTATTACCGTGGAGCAGCTGGTGCGCTGATGGTCTACGATATTACCAGGCG
Seq C2 exon
CTCCACGTACAATCACCTGAGCAGCTGGCTTACCGACACTCGCAATCTCACCAATCCCAGCACTGTGATCTTTCTCATTGGCAACAAATCGGATCTGGAGAGCACTCGGGAGGTTACCTACGAGGAGGCCAAGGAGTTTGCCGACGAGAACGGCCTAATGTTTCTCGAAGCGAGCGCTATGAC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0015791-'4-6,'4-5,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.065
Domain overlap (PFAM):
C1:
PF0007117=Ras=PU(14.2=63.9)
A:
PF0007117=Ras=FE(37.0=100)
C2:
PF0007117=Ras=FE(37.7=100)
Main Inclusion Isoform:
FBpp0080200
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0080199, FBpp0310268
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAGCGCCATACAACTACA
R:
GTTCTCGTCGGCAAACTCCTT
Band lengths:
253-434
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)