DmeEX6015919 @ dm6
Exon Skipping
Gene
FBgn0027567 | CG8108
Description
This gene is referred to in FlyBase by the symbol DmelCG8108 (FBgn0027567). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:9864639..9870674. Its molecular function is unknown. The biological processes in which it is involved are not known. 14 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; embryonic/larval somatic muscle; Z disc. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; female sterile; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr3L:9868254-9870098:+
Coord C1 exon
chr3L:9868254-9868935
Coord A exon
chr3L:9868999-9869322
Coord C2 exon
chr3L:9869446-9870098
Length
324 bp
Sequences
Splice sites
3' ss Seq
ATTTCCTCATTGATCCGCAGGAG
3' ss Score
8.43
5' ss Seq
AGGGTGAGT
5' ss Score
9.25
Exon sequences
Seq C1 exon
AGAGCAAGAAGACTTCGCCTGGTAAAAAACGCAACAAGTCGGCCAACAACGAGGACAAGAGTGAGGCCGAAGGTAACGATGATGACGACGATGATGATGATGAGCACGGTGATGGCGATGACGATGATGACAAGGACCTAAATGAGTCCGATCCCAAGAGCGCCAAGGCCGATGACGCCTCCGATGACGAGGATGTCAAGGTGAAGGGCGACGGTGAGGACGGCGATGGTGACAAATCGGACGAAAAGGCCAAGTCATCGGTCGAGAAGTCAGGTAAGAAGAAGGACAAAGACGACGCGAAGGACTCCAAGTCCAAGAAGTCATCATCCACCAAGAAAGAGCGCACGTCTCGCAAGGACAAAGACAAGGAATCATCGGGCGATGATCGTAGCAAGGAGCGACGTAGCTCCCGTCATCGGGATGAGGACCACAACAACCGCAAACGCAGCTTCATCAAACTCATTTGCGTCCATTGCCGCATCAAGTGTGTTACATTTAAG
Seq A exon
GAGTATAACTACCATCTGAACTCGCGCTCCCACAAGAACTCCATGCGTCAGGTGGCCCTCAACCAGCGAGCTGACCTGCAGCGTATGCGTGCCCGCCAGCGCACCACACAGCGCGAGATCGAGGAGAATAGCAAGGAGGAGCACGAGTCGCGCTACTGTCGTCTGTGCCGCTTGGCCTACCGCCAGCCCAAGAATCTTCATCAGGCCTCCGAACACCACAAGACCATTAAGAAGTTCTTAATGCCCTATTGCGGCTCTTGCCATCTGGCCTTCAAGAATGCCATGCTCTACGAGAACCACCGCTGCTCCCTGGATCACATTAGG
Seq C2 exon
AACAAGGCCCGCAACGATGAATCCGGATCGGATGATAGCGTGGATGAGCGCGAGATAGATTTGAATAAATTCCACACTGTAGACTCGGTGGGCGAGATCGATGTGGACATGATCGACGCCGATGTAGATGCCATGGTCACCGAGGCGGAGGCCGCTCTGAAAAGCGAGGATGAGGAGACTCGCAAACGCGCTCTGATTGGACCGGACTATATAAAGGTCATAGAGGCATTCTACTGCGAGCTGTGCAATCACTATTCCGCCAAGGCTGATGATGTCTCGTTAGAGGACTACACCAAAAAGCATTGCATGCAGCACTCCCATGTGAAGGCTTTCCTGCGAAACAAGGAGGAGACCGAGAAGAAGAACAAGACGGAGGAGGGCGATGAGGACGATCACGATGATGACAAAAAGGCCGGTGATGATGACGCCGATGGCGATGAGGACATCGATGGCAAGTTAAACGAGGATGACGACGAGTACGATGATGATGGTGATGCAGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0027567-'7-12,'7-11,8-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.917 A=0.417 C2=0.661
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0076068
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0076069
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTCTCGCAAGGACAAAGAC
R:
CGTTTGCGAGTCTCCTCATCC
Band lengths:
344-668
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)