Special

DmeEX6017255 @ dm6

Exon Skipping

Gene
FBgn0036741 | CG7510
Description
The gene anchor is referred to in FlyBase by the symbol Dmelanchor (CG7510, FBgn0036741). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:17621824..17630971. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport; intracellular signal transduction. 9 alleles are reported. The phenotypes of these alleles manifest in: syncytium; cell; dorsal-ventral compartment boundary of imaginal disc; wing posterior compartment; wing disc posterior compartment. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality during development; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.
Coordinates
chr3L:17627087-17627804:+
Coord C1 exon
chr3L:17627087-17627252
Coord A exon
chr3L:17627315-17627554
Coord C2 exon
chr3L:17627613-17627804
Length
240 bp
Sequences
Splice sites
3' ss Seq
TATGTATTCTCTTCGTTCAGGTT
3' ss Score
8.88
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
ATTGGTGCTACCGCTCGTAATCCGACAGACGGTAAACATTATGCAGTCTGGCCAGAACTTCAACGACACCACCGAGCTGAGCACTTTTGGCTTTCTCTACGGCACCTTTCCAGCTGCCCCCGGGGCTTTCGTCATTGCGACACAGTACAACATGGAGGTTGAATTG
Seq A exon
GTTGCTCGAAGCATGGTTTTCTGTACATTCATCTCGGCACCGCTGATGTTTATATCAGCCAAAATGATATCGCTGACGAACCTGAAGCCATTGGACTATCTCCATGAGCTGGATGCCTTTTCGTTTGACATCAGCGTGGCCGGCGCGGCTGCCTGTTGTATCATGCTGGCATTGTTGATCGTGACGAAGCGCTTCAAGCGTATGCCCCAAAGAATAACTTTCTGTCTGGTGCTTTCTCAG
Seq C2 exon
CTCATGTGCTGCATAGGAGTAATCCTCTGGTCCAAGATGGAGCACGTGCACCGTTGGCCTTTGTACCTGCAGTTTCTTCTATTTAATATCGGAACATACAGCACTCGTCTGTGGACTGGTCTTTTGGCCATTTCATTGCTCTTCCTGCAGTGTCGCAGCTTGTGCTTTGTGCTGAAACTATGGCCCTATATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0036741-'6-5,'6-4,7-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0354713=Mem_trans=FE(16.0=100)
A:
PF0354713=Mem_trans=PD(5.2=22.5)
C2:
NO


Main Inclusion Isoform:
FBpp0305332


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0074947


Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGTGCTACCGCTCGTAATC
R:
ATGGCCAAAAGACCAGTCCAC
Band lengths:
296-536
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)