DreEX0015014 @ danRer10
Exon Skipping
Gene
ENSDARG00000074329 | arvcfa
Description
armadillo repeat gene deleted in velocardiofacial syndrome a [Source:ZFIN;Acc:ZDB-GENE-091113-43]
Coordinates
chr10:484407-488429:+
Coord C1 exon
chr10:484407-484572
Coord A exon
chr10:487789-487806
Coord C2 exon
chr10:488358-488429
Length
18 bp
Sequences
Splice sites
3' ss Seq
CGGCGCTGGTCTCTCCGCAGAGG
3' ss Score
10.04
5' ss Seq
AGTGTAAGT
5' ss Score
8.46
Exon sequences
Seq C1 exon
TCGGTGGAGAACTGTGTCTGTATCTTGCGTAATCTCTCCTACCATGTGCACAAAGAGGTTCCCGGAGCTGAGAAATTCCACATCCAGGCGGCCAGTCACAATGCCAAACCAGCAGGACACCACAAGAAGGACAAGCCGGACTGTTTTGGCGGACGGACAACCAAAG
Seq A exon
AGGAATGGTTCCATCAGT
Seq C2 exon
GCAAAAGACACGGAGCTGTAGAGAAGAAGAGCGGCGGTGCTGATCTGCCCAAGAGGAGTCTGCCGATGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074329_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.500 A=0.000 C2=0.440
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0051418=Arm=PU(0.1=0.0)
Main Inclusion Isoform:
ENSDART00000145220fB1343
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTCACAATGCCAAACCAGCA
R:
GCCGCTCTTCTTCTCTACAGC
Band lengths:
108-126
Functional annotations
There are 1 annotated functions for this event
PMID: 24644279
All four isoforms co-immunoprecipitate with p68. There is an alternative promoter (N-term) and an NLS (HsaEX0006131).
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]