DreEX6070553 @ danRer10
Exon Skipping
Gene
ENSDARG00000099184 | map2k6
Description
mitogen-activated protein kinase kinase 6 [Source:ZFIN;Acc:ZDB-GENE-010202-3]
Coordinates
chr12:36415069-36441773:+
Coord C1 exon
chr12:36415069-36415345
Coord A exon
chr12:36441463-36441532
Coord C2 exon
chr12:36441725-36441773
Length
70 bp
Sequences
Splice sites
3' ss Seq
CTTTTTTATTCTCTCTGCAGGTA
3' ss Score
12.96
5' ss Seq
TACGTAAGA
5' ss Score
6.14
Exon sequences
Seq C1 exon
TGGTTTCTTTGCAGAGCGGTTGCAGAAATCCCCCCGTTTTCGTTGCGTGCAATTGAAAGAGCAGCCTTTGCACGGAGAACAAGTTTACCGACGCCCAAAGGCTCCGAGTGCATGAAGATCGGGGCTTGTATTTTGCACCTTTGTTGCAAGCAAGCCCGCTTGAAGCCTCACTGCGAGGGATAGATGGAAGGAGGGAGCGACAAGGAAAGCAAAGTCTTTTGTGATTCCCCTTCCCCCAACCCTAAAGGGGAGATGTCCGTGCCAAGTAACGTTAGAG
Seq A exon
GTAAAAAGAAGCTTCCAAAAGAGCTCAAGCTTCCAAAAGAGGTGTTCGAGAAACCGGCACCTGCTCCTAC
Seq C2 exon
ACCCCCGAGAGACCTGGACTCCAAAGCCTACGTTACCATTGGAGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000099184-'0-3,'0-2,5-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.994 A=0.806 C2=0.412
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCACCTTTGTTGCAAGCAAG
R:
TTTGGAGTCCAGGTCTCTCGG
Band lengths:
169-239
Functional annotations
There are 1 annotated functions for this event
PMID: 26538579
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: bimolecular fluorescence complementation, filter binding. ELM ID: ELMI003289; ELM sequence: KKRNPGLKI; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]