RnoEX0052215 @ rn6
Exon Skipping
Gene
ENSRNOG00000004437 | Map2k6
Description
mitogen-activated protein kinase kinase 6 [Source:RGD Symbol;Acc:620666]
Coordinates
chr10:98706960-98792730:+
Coord C1 exon
chr10:98706960-98707282
Coord A exon
chr10:98782950-98783016
Coord C2 exon
chr10:98792682-98792730
Length
67 bp
Sequences
Splice sites
3' ss Seq
CCTTATGTCCTTCCCCATAGGCA
3' ss Score
12.2
5' ss Seq
CACGTAAGT
5' ss Score
10.16
Exon sequences
Seq C1 exon
TCTGCGCACTAAGATACTCAGTTCCAAGTTTGGAGCTTTTAGCTGCCAGCCCTGGCCCATCATGTAGCTGCAGCACAGCCTTCCCTAACGTTGCAATTGGGGGAAAAATCACTTTCCAGACTGTTTTGCAAGGTGTGCAATTCCATCTTGACTCCCTGAAAGTCCATCTGCTGCATCGGTCAAGAGAAACTCCACTTGCATGAAGATTGCACGCCTGCAGCTTGCATCTTTGTTGCAAAACTAGCTACAGAAGAGAAGCAAGGCAAAGTCTTTTGTGCTCCCCTCCCCCATCAAAGGAAAGGGGAAAATGTCTCAGTCGAAAG
Seq A exon
GCAAGAAGCGAAACCCCGGCCTTAAGATTCCAAGGGAAGCGTTTGAACAACCTCAGACCAGTTCCAC
Seq C2 exon
GCCGCCTCGGGATTTAGACTCCAAGGCTTGCATTTCTATTGGAAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000004437-'1-3,'1-1,10-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.471
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCTGCTGCATCGGTCAAGA
R:
TGGAGTCTAAATCCCGAGGCG
Band lengths:
182-249
Functional annotations
There are 1 annotated functions for this event
PMID: 26538579
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: bimolecular fluorescence complementation, filter binding. ELM ID: ELMI003289; ELM sequence: KKRNPGLKI; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]