HsaEX6024519 @ hg19
Exon Skipping
Gene
ENSG00000108984 | MAP2K6
Description
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:6846]
Coordinates
chr17:67501012-67513044:+
Coord C1 exon
chr17:67501012-67501027
Coord A exon
chr17:67501921-67501987
Coord C2 exon
chr17:67512996-67513044
Length
67 bp
Sequences
Splice sites
3' ss Seq
CCTTTTGTCTTTCCCCATAGGCA
3' ss Score
13.59
5' ss Seq
CACGTAAGT
5' ss Score
10.16
Exon sequences
Seq C1 exon
CTGGAACAGGGAAAAT
Seq A exon
GCAAGAAGCGAAACCCTGGCCTTAAAATTCCAAAAGAAGCATTTGAACAACCTCAGACCAGTTCCAC
Seq C2 exon
ACCACCTCGAGATTTAGACTCCAAGGCTTGCATTTCTATTGGAAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108984-'2-3,'2-2,3-3=AN
Average complexity
A_C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.833 A=0.957 C2=0.471
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 26538579
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: bimolecular fluorescence complementation, filter binding. ELM ID: ELMI003289; ELM sequence: KKRNPGLKI; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)