BtaEX0021220 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000001609 | MAP2K6
Description
Bos taurus mitogen-activated protein kinase kinase 6 (MAP2K6), mRNA. [Source:RefSeq mRNA;Acc:NM_001034045]
Coordinates
chr19:61733126-61814973:-
Coord C1 exon
chr19:61814693-61814973
Coord A exon
chr19:61743634-61743700
Coord C2 exon
chr19:61733126-61733174
Length
67 bp
Sequences
Splice sites
3' ss Seq
CCTTCCATCTTTCCCTGTAGGCA
3' ss Score
12.25
5' ss Seq
CACGTAAGT
5' ss Score
10.16
Exon sequences
Seq C1 exon
CTGCCAGCCCTGGCCCATCATGTAGCTGCAGCACAGCCTTCCCTAACGTTGCAACTGGGGGAAAAATCACTTTCCAGTCTGCTTTGCAAGGCGTGCATTTCCATCTGGATCCCCTGGAAGTCCATCTGCTGCCTCGGTCAAGAGAAACTCCACTTGCATGAAGATTGCACGCCTGCAGCTTGCATCTTTGTTGCAAAACTAGCTACAGAAGAGAAGCCAGGCAAAGTCTTTTGTGCTCCCCTCCCCCATCAAAGGAAAGGGGAAAATGTCTCAGTCGAAAG
Seq A exon
GCAAGAAGCGAAACCCTGGCCTTAAAATTCCCAAAGAAGCATTTGAACAACCTCAGACCAGTTCCAC
Seq C2 exon
GCCGCCGCGGGATTTAGACTCCAAAGCTTGCATTTCTATTGGAAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000001609_MULTIEX1-3/3=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.944 A=0.944 C2=0.591
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTCGGTCAAGAGAAACTCC
R:
TTTGGAGTCTAAATCCCGCGG
Band lengths:
176-243
Functional annotations
There are 1 annotated functions for this event
PMID: 26538579
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: bimolecular fluorescence complementation, filter binding. ELM ID: ELMI003289; ELM sequence: KKRNPGLKI; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development