DreEX6074535 @ danRer10
Exon Skipping
Gene
ENSDARG00000023472 | ctnnb2
Description
catenin, beta 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2575]
Coordinates
chr19:48327025-48329153:-
Coord C1 exon
chr19:48329003-48329153
Coord A exon
chr19:48327164-48327285
Coord C2 exon
chr19:48327025-48327085
Length
122 bp
Sequences
Splice sites
3' ss Seq
TCTGCTGTTCATCTCTGCAGCCA
3' ss Score
9.21
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
CTGCTGTATTCCCCCATCGAGAACATCCAGCGTGTAGCAGCGGGCGTCCTCTGTGAGCTGGCGCAGGATAAGGAGGCGGCGGAGGCCATCGAGGCTGAAGGAGCCACAGCTCCACTCACTGAACTGCTGCACTCCAGGAACGAGGGCGTGG
Seq A exon
CCACATACGCCGCAGCCGTGCTCTTCCGCATGTCTGAGGACAAACCACAGGACTATAAGAAGCGTCTGTCAGTGGAGCTCACCAGCTCACTCTTCAGAACCGAGCCCATGGCCTGGAATGAG
Seq C2 exon
ACTGCTGATCTAGGTCTGGATATCGGTGCTCCAGGAGAGACACTCGCATACAGAGCAGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000023472-'25-25,'25-24,30-25=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
NA
No structure available
Features
Disorder rate (Iupred):
C1=0.059 A=0.024 C2=0.095
Domain overlap (PFAM):
C1:
PF0051418=Arm=PD(51.2=41.2),PF0051418=Arm=PU(68.3=54.9)
A:
PF0051418=Arm=PD(29.3=29.3)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTGTATTCCCCCATCGAGA
R:
CGTCTGCTCTGTATGCGAGTG
Band lengths:
211-333
Functional annotations
There are 1 annotated functions for this event
PMID: 16476742
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, protein kinase assay, western blot. ELM ID: ELMI001503; ELM sequence: KRLSVEL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]