HsaEX0002433 @ hg38
Exon Skipping
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]
Coordinates
chr9:133436829-133438366:+
Coord C1 exon
chr9:133436829-133436955
Coord A exon
chr9:133437749-133437897
Coord C2 exon
chr9:133438246-133438366
Length
149 bp
Sequences
Splice sites
3' ss Seq
TTTTCACTCTGCCCTCCCAGGGG
3' ss Score
9.47
5' ss Seq
AGGGTAGGC
5' ss Score
7.26
Exon sequences
Seq C1 exon
GCCTGCGAGAAGACCCAGCTGGAGTTCATGTCGCAACAGTGCGCCAGGACCGACGGCCAGCCGCTGCGCTCCTCCCCTGGCGGCGCCTCCTTCTACCACTGGGGTGCTGCTGTACCACACAGCCAAG
Seq A exon
GGGATGCTCTGTGCAGACACATGTGCCGGGCCATTGGCGAGAGCTTCATCATGAAGCGTGGAGACAGCTTCCTCGATGGGACCCGGTGTATGCCAAGTGGCCCCCGGGAGGACGGGACCCTGAGCCTGTGTGTGTCGGGCAGCTGCAGG
Seq C2 exon
ACATTTGGCTGTGATGGTAGGATGGACTCCCAGCAGGTATGGGACAGGTGCCAGGTGTGTGGTGGGGACAACAGCACGTGCAGCCCACGGAAGGGCTCTTTCACAGCTGGCAGAGCGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-'21-23,'21-22,22-23=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.023 A=0.040 C2=0.024
Domain overlap (PFAM):
C1:
PF0009014=TSP_1=PD(1.9=2.3)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGCGAGAAGACCCAGCT
R:
GCTCTGCCAGCTGTGAAAGAG
Band lengths:
242-391
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development