HsaEX0004098 @ hg19
Exon Skipping
Gene
ENSG00000154188 | ANGPT1
Description
angiopoietin 1 [Source:HGNC Symbol;Acc:484]
Coordinates
chr8:108306164-108334356:-
Coord C1 exon
chr8:108334124-108334356
Coord A exon
chr8:108315468-108315595
Coord C2 exon
chr8:108306164-108306265
Length
128 bp
Sequences
Splice sites
3' ss Seq
CTTTTTTTTTTTTTTTGCAGTTT
3' ss Score
10.92
5' ss Seq
AAGGTAAAA
5' ss Score
8.38
Exon sequences
Seq C1 exon
TTTATTAGAACATAAAATCTTAGAAATGGAAGGAAAACACAAGGAAGAGTTGGACACCTTAAAGGAAGAGAAAGAGAACCTTCAAGGCTTGGTTACTCGTCAAACATATATAATCCAGGAGCTGGAAAAGCAATTAAACAGAGCTACCACCAACAACAGTGTCCTTCAGAAGCAGCAACTGGAGCTGATGGACACAGTCCACAACCTTGTCAATCTTTGCACTAAAGAAGGTG
Seq A exon
TTTTACTAAAGGGAGGAAAAAGAGAGGAAGAGAAACCATTTAGAGACTGTGCAGATGTATATCAAGCTGGTTTTAATAAAAGTGGAATCTACACTATTTATATTAATAATATGCCAGAACCCAAAAAG
Seq C2 exon
GTGTTTTGCAATATGGATGTCAATGGGGGAGGTTGGACTGTAATACAACATCGTGAAGATGGAAGTCTAGATTTCCAAAGAGGCTGGAAGGAATATAAAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000154188_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.214 A=0.000 C2=0.018
Domain overlap (PFAM):
C1:
PF097384=DUF2051=PU(66.0=94.3),PF089195=F_actin_bind=WD(100=70.0)
A:
PF089195=F_actin_bind=PD(1.9=2.3),PF0014713=Fibrinogen_C=PU(14.0=69.8)
C2:
PF0014713=Fibrinogen_C=FE(15.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACACAAGGAAGAGTTGGACACC
R:
ATTACAGTCCAACCTCCCCCA
Band lengths:
242-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)