HsaEX0004137 @ hg19
Exon Skipping
Gene
ENSG00000145362 | ANK2
Description
ankyrin 2, neuronal [Source:HGNC Symbol;Acc:493]
Coordinates
chr4:114267056-114284625:+
Coord C1 exon
chr4:114267056-114267178
Coord A exon
chr4:114281979-114282053
Coord C2 exon
chr4:114284494-114284625
Length
75 bp
Sequences
Splice sites
3' ss Seq
CTGTTTTTGACCTTCTCCAGATC
3' ss Score
9.78
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
Exon sequences
Seq C1 exon
GTACGCGATACGACTCAGGAACCTTGCGGACGACTATCATTTATGAAGGAGCCAAAATCCACGAGAGGCCTGGTGCATCAAGCTATTTGCAACTTAAACATCACTTTGCCGATTTATACAAAG
Seq A exon
ATCCACAGGATGAGCAGGAACGGATCGAGGAAAGGCTGGCTTATATTGCTGATCACCTTGGCTTCAGCTGGACAG
Seq C2 exon
AATTAGCAAGAGAACTGGATTTCACTGAGGAGCAAATTCATCAAATTCGAATTGAAAATCCCAACTCTCTTCAAGACCAGAGTCATGCACTGTTGAAGTACTGGCTAGAGAGGGATGGGAAACATGCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145362_MULTIEX1-4/4=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.117 A=0.398 C2=0.160
Domain overlap (PFAM):
C1:
PF103904=ELL=FE(32.8=100)
A:
PF103904=ELL=FE(20.0=100),PF0053117=Death=PU(30.0=57.7)
C2:
PF103904=ELL=PD(2.4=8.6),PF0053117=Death=FE(68.0=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCCTGGTGCATCAAGCTATT
R:
TCCCATCCCTCTCTAGCCAGT
Band lengths:
177-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)