HsaEX0015431 @ hg38
Exon Skipping
Gene
ENSG00000122966 | CIT
Description
citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]
Coordinates
chr12:119713203-119714334:-
Coord C1 exon
chr12:119714197-119714334
Coord A exon
chr12:119713468-119713648
Coord C2 exon
chr12:119713203-119713294
Length
181 bp
Sequences
Splice sites
3' ss Seq
TGCTCACTGTTCTTCCCTAGAAT
3' ss Score
9.55
5' ss Seq
CAGGTACCA
5' ss Score
7.88
Exon sequences
Seq C1 exon
AATTTAGTCGGCGTCTTAAGGAACGCATGCACCACAATATTCCTCACCGATTCAACGTAGGACTGAACATGCGAGCCACAAAGTGTGCTGTGTGTCTGGATACCGTGCACTTTGGACGCCAGGCATCCAAATGTCTCG
Seq A exon
AATGTCAGGTGATGTGTCACCCCAAGTGCTCCACGTGCTTGCCAGCCACCTGCGGCTTGCCTGCTGAATATGCCACACACTTCACCGAGGCCTTCTGCCGTGACAAAATGAACTCCCCAGGTCTCCAGACCAAGGAGCCCAGCAGCAGCTTGCACCTGGAAGGGTGGATGAAGGTGCCCAG
Seq C2 exon
GAATAACAAACGAGGACAGCAAGGCTGGGACAGGAAGTACATTGTCCTGGAGGGATCAAAAGTCCTCATTTATGACAATGAAGCCAGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122966_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.364 A=0.246 C2=0.063
Domain overlap (PFAM):
C1:
PF0013017=C1_1=PU(59.6=66.0)
A:
PF0013017=C1_1=PD(38.5=32.8),PF0016924=PH=PU(8.3=16.4)
C2:
PF0016924=PH=FE(25.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAGTCGGCGTCTTAAGGAACG
R:
CTTCTCTGGCTTCATTGTCATAAA
Band lengths:
226-407
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development