HsaEX0015683 @ hg19
Exon Skipping
Gene
ENSG00000106665 | CLIP2
Description
CAP-GLY domain containing linker protein 2 [Source:HGNC Symbol;Acc:2586]
Coordinates
chr7:73778585-73791152:+
Coord C1 exon
chr7:73778585-73778645
Coord A exon
chr7:73787262-73787366
Coord C2 exon
chr7:73790217-73791152
Length
105 bp
Sequences
Splice sites
3' ss Seq
GTCCACCCTGGGTGGACCAGACC
3' ss Score
0.66
5' ss Seq
AGGGTAACC
5' ss Score
5.4
Exon sequences
Seq C1 exon
GAAGGTGGAGGATCTGCAGTTCCGCGTGGAGGAGGAGTCCATCACCAAGGGAGACCTGGAG
Seq A exon
ACCCAGACGCAGCTGGAGCACGCGCGCATTGGGGAGCTGGAACAGAGCCTGCTACTGGAGAAGGCGCAGGCCGAGCGGCTGCTCCGAGAATTAGCGGACAACAGG
Seq C2 exon
CTGACCACAGTGGCCGAGAAGTCGCGCGTGCTGCAGCTGGAGGAGGAGCTCACCCTGCGCCGAGGTGAAATCGAGGAGCTCCAGCAGTGCCTGTTGCACTCGGGTCCCCCACCTCCGGACCACCCAGACGCCGCCGAGATCCTGCGGCTACGGGAGCGGCTGCTCTCGGCCAGCAAGGAACACCAGAGGGAGAGTGGGGTGCTGCGGGATAAATACGAGAAGGCCCTGAAGGCCTACCAGGCGGAGGTGGACAAGCTCCGCGCGGCCAACGAGAAGTACGCACAGGAGGTGGCGGGCCTGAAGGACAAGGTTCAGCAGGCCACCAGCGAGAACATGGGGCTAATGGACAACTGGAAATCCAAGCTGGACTCGCTGGCCTCGGACCACCAGAAGTCCCTGGAGGACCTCAAAGCCACCCTGAACTCGGGCCCAGGCGCCCAGCAGAAGGAGATCGGCGAGCTGAAGGCAGTGATGGAGGGCATCAAGATGGAGCACCAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106665_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.171 A=0.143 C2=0.447
Domain overlap (PFAM):
C1:
PF116003=CAF-1_p150=FE(10.6=100)
A:
PF0396210=Mnd1=PU(0.8=2.9)
C2:
PF116003=CAF-1_p150=PD(11.6=7.1),PF093685=Sas10=WD(100=19.6),PF0017016=bZIP_1=WD(100=19.9)
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAGTCCATCACCAAGGGAG
R:
GTATTTATCCCGCAGCACCCC
Band lengths:
245-350
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
It does NOT significantly modify interaction with CLASP1, CLASP2 and itself. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)