HsaEX0015683 @ hg38
Exon Skipping
Gene
ENSG00000106665 | CLIP2
Description
CAP-Gly domain containing linker protein 2 [Source:HGNC Symbol;Acc:HGNC:2586]
Coordinates
chr7:74364255-74376822:+
Coord C1 exon
chr7:74364255-74364315
Coord A exon
chr7:74372932-74373036
Coord C2 exon
chr7:74375887-74376822
Length
105 bp
Sequences
Splice sites
3' ss Seq
GTCCACCCTGGGTGGACCAGACC
3' ss Score
0.66
5' ss Seq
AGGGTAACC
5' ss Score
5.4
Exon sequences
Seq C1 exon
GAAGGTGGAGGATCTGCAGTTCCGCGTGGAGGAGGAGTCCATCACCAAGGGAGACCTGGAG
Seq A exon
ACCCAGACGCAGCTGGAGCACGCGCGCATTGGGGAGCTGGAACAGAGCCTGCTACTGGAGAAGGCGCAGGCCGAGCGGCTGCTCCGAGAATTAGCGGACAACAGG
Seq C2 exon
CTGACCACAGTGGCCGAGAAGTCGCGCGTGCTGCAGCTGGAGGAGGAGCTCACCCTGCGCCGAGGTGAAATCGAGGAGCTCCAGCAGTGCCTGTTGCACTCGGGTCCCCCACCTCCGGACCACCCAGACGCCGCCGAGATCCTGCGGCTACGGGAGCGGCTGCTCTCGGCCAGCAAGGAACACCAGAGGGAGAGTGGGGTGCTGCGGGATAAATACGAGAAGGCCCTGAAGGCCTACCAGGCGGAGGTGGACAAGCTCCGCGCGGCCAACGAGAAGTACGCACAGGAGGTGGCGGGCCTGAAGGACAAGGTTCAGCAGGCCACCAGCGAGAACATGGGGCTAATGGACAACTGGAAATCCAAGCTGGACTCGCTGGCCTCGGACCACCAGAAGTCCCTGGAGGACCTCAAAGCCACCCTGAACTCGGGCCCAGGCGCCCAGCAGAAGGAGATCGGCGAGCTGAAGGCAGTGATGGAGGGCATCAAGATGGAGCACCAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106665_MULTIEX4-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.190 A=0.143 C2=0.447
Domain overlap (PFAM):
C1:
NO
A:
PF0396210=Mnd1=PU(0.1=0.0)
C2:
PF0396210=Mnd1=PD(98.4=39.1),PF093685=Sas10=WD(100=19.6),PF153971=DUF4618=WD(100=33.7)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAGTCCATCACCAAGGGAG
R:
GTATTTATCCCGCAGCACCCC
Band lengths:
245-350
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
It does NOT significantly modify interaction with CLASP1, CLASP2 and itself. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development