HsaEX0019075 @ hg19
Exon Skipping
Gene
ENSG00000140995 | DEF8
Description
differentially expressed in FDCP 8 homolog (mouse) [Source:HGNC Symbol;Acc:25969]
Coordinates
chr16:90015183-90021674:+
Coord C1 exon
chr16:90015183-90015222
Coord A exon
chr16:90020651-90020784
Coord C2 exon
chr16:90021577-90021674
Length
134 bp
Sequences
Splice sites
3' ss Seq
TGGCCCTGCCTGGCCCTCAGGTG
3' ss Score
8.44
5' ss Seq
AAGGTGGGT
5' ss Score
8.23
Exon sequences
Seq C1 exon
ATCCAGCGCAGCCGGGAGACAGATGCGAGGCGGCGGTCAG
Seq A exon
GTGGGATGCTATGGAATATGATGAGAAGCTGGCCCGTTTCCGGCAGGCCCACCTCAACCCCTTCAACAAGCAGTCTGGGCCGAGACAGCATGAGCAGGGCCCTGGGGAGGAGGTCCCGGACGTCACTCCTGAAG
Seq C2 exon
AGGCCCTGCCTGAGCTGCCCCCTGGGGAGCCGGAATTCCGCTGCCCTGAACGCGTGATGGATCTCGGCCTGTCTGAGGACCACTTCTCCCGCCCTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140995_MULTIEX1-5/5=C1-C2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.706 C2=0.503
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF119173=DUF3435=PU(3.1=21.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGCCGGGAGACAGATG
R:
ACAGGGCGGGAGAAGTGG
Band lengths:
130-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)