HsaEX0019095 @ hg19
Exon Skipping
Gene
ENSG00000119522 | DENND1A
Description
DENN/MADD domain containing 1A [Source:HGNC Symbol;Acc:29324]
Coordinates
chr9:126519982-126554909:-
Coord C1 exon
chr9:126554866-126554909
Coord A exon
chr9:126531793-126531842
Coord C2 exon
chr9:126519982-126520101
Length
50 bp
Sequences
Splice sites
3' ss Seq
ATCTCTCTTTCTCTCCACAGGAA
3' ss Score
14.04
5' ss Seq
CAGGTAGTG
5' ss Score
6.13
Exon sequences
Seq C1 exon
ATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAG
Seq A exon
GAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAG
Seq C2 exon
CCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119522_MULTIEX1-2/7=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.085 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0345613=uDENN=PU(21.1=53.3)
A:
PF0345613=uDENN=FE(28.6=100),PF0306810=PAD=FE(21.9=100)
C2:
PF0345613=uDENN=PD(52.7=70.7),PF0214116=DENN=PU(13.0=22.0)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGAGGCAATTCCCGGAG
R:
TTCGCTCCTGAAGATAAGCGG
Band lengths:
133-183
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)