HsaEX0020458 @ hg38
Exon Skipping
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]
Coordinates
chr1:172081832-172131288:+
Coord C1 exon
chr1:172081832-172081902
Coord A exon
chr1:172092824-172092875
Coord C2 exon
chr1:172131175-172131288
Length
52 bp
Sequences
Splice sites
3' ss Seq
CTTTCCTTTGCTTTTCTCAGTGC
3' ss Score
9.49
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
Exon sequences
Seq C1 exon
GTATTGCTATTGATTGACATTCAAGTCTCTTACATCAACACCAACCATGAAGACTTCATTGGCTTCGCAAA
Seq A exon
TGCTCAGCAGAGGAGCAGTCAGGTTCACAAGAAAACCACAGTTGGAAATCAG
Seq C2 exon
GTGATTCGCAAGGGGTGGCTCACCATCAGCAACATTGGCATCATGAAAGGCGGCTCGAAGGGATACTGGTTCGTCCTTACTGCGGAAAGCTTGTCCTGGTATAAAGATGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959-'28-47,'28-40,29-47
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.102 C2=0.000
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(7.8=100)
A:
PF0103115=Dynamin_M=PD(4.1=66.7)
C2:
PF0016924=PH=PU(35.6=97.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATCAACACCAACCATGAAGACT
R:
AAGCTTTCCGCAGTAAGGACG
Band lengths:
132-184
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development