HsaEX0020460 @ hg19
Exon Skipping
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:29125]
Coordinates
chr1:172277868-172348322:+
Coord C1 exon
chr1:172277868-172277979
Coord A exon
chr1:172292469-172292480
Coord C2 exon
chr1:172348158-172348322
Length
12 bp
Sequences
Splice sites
3' ss Seq
CCTTGCGGCTACATGCATAGGGG
3' ss Score
4.06
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
Exon sequences
Seq C1 exon
GAATGTATACAAAGACTATCGCTTCCTTGAGCTGGCATGTGATTCCCAGGAGGATGTCGACAGCTGGAAGGCATCTCTACTAAGAGCTGGGGTCTATCCTGACAAATCTGTA
Seq A exon
GGGAACAACAAA
Seq C2 exon
GCTGAAAATGATGAGAATGGACAAGCAGAAAACTTTTCCATGGACCCACAATTGGAGAGGCAAGTGGAGACCATTCGCAACCTCGTAGACTCCTACATGTCCATTATCAACAAATGTATCCGAGATCTAATTCCAAAAACAATAATGCACCTTATGATCAATAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959-MICROEX1
Average complexity
MIC_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.015 A=1.000 C2=0.297
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(27.9=76.3)
A:
NO
C2:
PF0221213=GED=PU(41.3=69.1)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCTGGGGTCTATCCTGACA
R:
CGAATGGTCTCCACTTGCCTC
Band lengths:
106-118
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)