HsaEX0020682 @ hg38
Exon Skipping
Gene
ENSG00000147443 | DOK2
Description
docking protein 2 [Source:HGNC Symbol;Acc:HGNC:2991]
Coordinates
chr8:21910673-21912510:-
Coord C1 exon
chr8:21912229-21912510
Coord A exon
chr8:21911901-21911988
Coord C2 exon
chr8:21910673-21910857
Length
88 bp
Sequences
Splice sites
3' ss Seq
ACGGGGCGCCTCCTCCCTAGGGG
3' ss Score
7.71
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
AAATGGCGCCGCTTCGGCGCCTCACTGTATGGAGGGTCGGACTGCGCCTTGGCCCGGCTGGAGCTGCAGGAGGGCCCGGAGAAGCCTCGTCGGTGTGAGGCTGCCCGGAAGGTCATCCGCCTCAGTGACTGCCTGCGGGTGGCCGAGGCCGGCGGAGAGGCCAGCAGCCCCCGGGACACCAGTGCCTTCTTCCTGGAGACCAAGGAGCGCCTGTACCTCCTGGCGGCCCCTGCAGCGGAGCGCGGCGACTGGGTGCAGGCCATCTGCCTCCTGGCCTTCCCC
Seq A exon
GGGCAGAGGAAGGAGCTCTCGGGGCCAGAGGGAAAGCAGAGCCGGCCCTGCATGGAGGAAAATGAATTGTACAGCAGCGCAGTCACAG
Seq C2 exon
TCGGCCCCCACAAGGAATTTGCTGTGACCATGAGACCTACAGAAGCCAGTGAGAGGTGCCACCTGCGGGGGTCCTATACCCTCCGGGCTGGGGAGAGTGCCCTGGAGCTGTGGGGTGGGCCCGAGCCAGGGACCCAGCTGTACGACTGGCCCTACAGGTTTCTGCGGCGCTTTGGGCGGGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147443-'1-11,'1-6,3-11
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.028 A=0.450 C2=0.161
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(83.5=96.8)
A:
NO
C2:
PF0217412=IRS=PU(58.4=95.2)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACACCAGTGCCTTCTTCCTG
R:
GCACCTCTCACTGGCTTCTGT
Band lengths:
167-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development