HsaEX0032448 @ hg38
Exon Skipping
Gene
ENSG00000259207 | ITGB3
Description
integrin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6156]
Coordinates
chr17:47274419-47284695:+
Coord C1 exon
chr17:47274419-47274504
Coord A exon
chr17:47283354-47283549
Coord C2 exon
chr17:47284443-47284695
Length
196 bp
Sequences
Splice sites
3' ss Seq
TTTGGGCTCCTGTCTTACAGGCC
3' ss Score
9.92
5' ss Seq
CAGGTAGGG
5' ss Score
9.46
Exon sequences
Seq C1 exon
GGCCCAACATCTGTACCACGCGAGGTGTGAGCTCCTGCCAGCAGTGCCTGGCTGTGAGCCCCATGTGTGCCTGGTGCTCTGATGAG
Seq A exon
GCCCTGCCTCTGGGCTCACCTCGCTGTGACCTGAAGGAGAATCTGCTGAAGGATAACTGTGCCCCAGAATCCATCGAGTTCCCAGTGAGTGAGGCCCGAGTACTAGAGGACAGGCCCCTCAGCGACAAGGGCTCTGGAGACAGCTCCCAGGTCACTCAAGTCAGTCCCCAGAGGATTGCACTCCGGCTCCGGCCAG
Seq C2 exon
ATGATTCGAAGAATTTCTCCATCCAAGTGCGGCAGGTGGAGGATTACCCTGTGGACATCTACTACTTGATGGACCTGTCTTACTCCATGAAGGATGATCTGTGGAGCATCCAGAACCTGGGTACCAAGCTGGCCACCCAGATGCGAAAGCTCACCAGTAACCTGCGGATTGGCTTCGGGGCATTTGTGGACAAGCCTGTGTCACCATACATGTATATCTCCCCACCAGAGGCCCTCGAAAACCCCTGCTATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000259207_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.242 C2=0.000
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PU(4.0=58.6)
A:
PF0036213=Integrin_beta=FE(15.3=100)
C2:
PF0036213=Integrin_beta=FE(19.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAACATCTGTACCACGCGAGG
R:
CGCAGGTTACTGGTGAGCTTT
Band lengths:
248-444
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development