HsaEX0032482 @ hg38
Exon Skipping
Gene
ENSG00000115221 | ITGB6
Description
integrin subunit beta 6 [Source:HGNC Symbol;Acc:HGNC:6161]
Coordinates
chr2:160112080-160137851:-
Coord C1 exon
chr2:160137434-160137851
Coord A exon
chr2:160123791-160123888
Coord C2 exon
chr2:160112080-160112199
Length
98 bp
Sequences
Splice sites
3' ss Seq
CTGTTGGATACTGTCCACAGGAG
3' ss Score
6.08
5' ss Seq
AAGGTTCTG
5' ss Score
2.04
Exon sequences
Seq C1 exon
GCTTCCTTCAGCGTGACTGTGAATATCCCACACTGCGAGAGAAGAAGCAGGCACATTATCATAAAGCCTGTGGGGCTGGGGGATGCCCTGGAATTACTTGTCAGCCCAGAATGCAACTGCGACTGTCAGAAAGAAGTGGAAGTGAACAGCTCCAAATGTCACCACGGGAACGGCTCTTTCCAGTGTGGGGTGTGTGCCTGCCACCCTGGCCACATGGGGCCTCGCTGTGAGTGTGGCGAGGACATGCTGAGCACAGATTCCTGCAAGGAGGCCCCAGATCATCCCTCCTGCAGCGGAAGGGGTGACTGCTACTGTGGGCAGTGTATCTGCCACTTGTCTCCCTATGGAAACATTTATGGGCCTTATTGCCAGTGTGACAATTTCTCCTGCGTGAGACACAAAGGGCTGCTCTGCGGAG
Seq A exon
GAGCTGCATTGAGTGCCACCTGTCAGCAGCTGGCCAAGCCCGAGAAGAATGTGTGGACAAGTGCAAACTAGCTGGTGCGACCATCAGTGAAGAAGAAG
Seq C2 exon
ATTTCTCAAAGGATGGTTCTGTTTCCTGCTCTCTGCAAGGAGAAAATGAATGTCTTATTACATTCCTAATAACTACAGATAATGAGGGGAAAACCATCATTCACAGCATCAATGAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115221_MULTIEX1-2/2=C1-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PD(11.9=29.3),PF079748=EGF_2=PU(32.3=7.1)
A:
PF079657=Integrin_B_tail=FE(39.3=100)
C2:
PF079657=Integrin_B_tail=FE(47.6=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCAGATCATCCCTCCTGCAG
R:
GCAGAGAGCAGGAAACAGAACC
Band lengths:
182-280
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development