HsaEX0036934 @ hg38
Exon Skipping
Gene
ENSG00000168056 | LTBP3
Description
latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:HGNC:6716]
Coordinates
chr11:65540013-65540614:-
Coord C1 exon
chr11:65540486-65540614
Coord A exon
chr11:65540245-65540382
Coord C2 exon
chr11:65540013-65540153
Length
138 bp
Sequences
Splice sites
3' ss Seq
CACGCTTTTCCTCCCTGCAGACG
3' ss Score
12.26
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
Exon sequences
Seq C1 exon
ACATCGACGAGTGCATGTTGTTCGGGTCGGAGATTTGCAAGGAGGGCAAGTGCGTGAACACGCAGCCTGGCTACGAGTGCTACTGCAAGCAGGGCTTCTACTACGACGGGAACCTGCTGGAATGCGTGG
Seq A exon
ACGTGGACGAGTGCCTGGACGAGTCCAACTGCCGGAACGGAGTGTGTGAGAACACGCGCGGCGGCTACCGCTGTGCCTGCACGCCCCCTGCCGAGTACAGTCCCGCGCAGCGCCAGTGCCTGAGCCCGGAAGAGATGG
Seq C2 exon
ACGTGGACGAGTGCCAGGACCCGGCAGCCTGCCGCCCTGGCCGCTGCGTCAACCTGCCGGGCTCCTACCGCTGCGAGTGTCGCCCGCCCTGGGTGCCCGGGCCCTCCGGCCGCGATTGCCAGCTCCCCGAGAGCCCGGCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168056-'49-74,'49-73,50-74
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.037 C2=0.188
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)
A:
PF0764510=EGF_CA=WD(100=85.1),PF0764510=EGF_CA=PU(0.1=0.0)
C2:
PF0764510=EGF_CA=WD(100=83.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCGGGTCGGAGATTTGCAAG
R:
CTCTCGGGGAGCTGGCAATC
Band lengths:
242-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development