HsaEX0037507 @ hg38
Exon Skipping
Gene
ENSG00000108984 | MAP2K6
Description
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6846]
Coordinates
chr17:69526570-69543331:+
Coord C1 exon
chr17:69526570-69526709
Coord A exon
chr17:69536115-69536160
Coord C2 exon
chr17:69541676-69543331
Length
46 bp
Sequences
Splice sites
3' ss Seq
ATTATTTTTTTTTCTTTAAGCTT
3' ss Score
8.12
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
ATTGAGTTGGCCATCCTTCGATTTCCCTATGATTCATGGGGAACTCCATTTCAGCAGCTCAAACAGGTGGTAGAGGAGCCATCGCCACAACTCCCAGCAGACAAGTTCTCTGCAGAGTTTGTTGACTTTACCTCACAGTG
Seq A exon
CTTAAAGAAGAATTCCAAAGAACGGCCTACATACCCAGAGCTAATG
Seq C2 exon
CAACATCCATTTTTCACCCTACATGAATCCAAAGGAACAGATGTGGCATCTTTTGTAAAACTGATTCTTGGAGACTAAAAAGCAGTGGACTTAATCGGTTGACCCTACTGTGGATTGGTGGGTTTCGGGGTGAAGCAAGTTCACTACAGCATCAATAGAAAGTCATCTTTGAGATAATTTAACCCTGCCTCTCAGAGGGTTTTCTCTCCCAATTTTCTTTTTACTCCCCCTCTTAAGGGGGCCTTGGAATCTATAGTATAGAATGAACTGTCTAGATGGATGAATTATGATAAAGGCTTAGGACTTCAAAAGGTGATTAAATATTTAATGATGTGTCATATGAGTCCTCAAGCTTCTCAGACTTCTCTTATTCTTTACAAAATGAATGCATTGGCCCTGACAAAAAGGTGCTACGGTAGTGATGAAATTATAAGTAGATTTGTAGTTTGTCCCATTTATTATTTTAATATTTATGTTTAAGTGCTTGGTTGAAAAGATTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108984-'32-36,'32-34,35-36
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.028 A=0.046 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(17.8=100)
A:
PF0006920=Pkinase=FE(5.8=100)
C2:
PF0006920=Pkinase=PD(1.6=15.4)
Main Skipping Isoform:
ENST00000589647fB19406
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTCAAACAGGTGGTAGAGGA
R:
TGCCACATCTGTTCCTTTGGA
Band lengths:
133-179
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development