HsaEX0038725 @ hg19
Exon Skipping
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF-like-domains 10 [Source:HGNC Symbol;Acc:29634]
Coordinates
chr5:126676222-126732470:+
Coord C1 exon
chr5:126676222-126676322
Coord A exon
chr5:126705602-126705694
Coord C2 exon
chr5:126732224-126732470
Length
93 bp
Sequences
Splice sites
3' ss Seq
ATTGATTTTCTCTCTGACAGCCC
3' ss Score
8.28
5' ss Seq
GTGGTAAGT
5' ss Score
10.36
Exon sequences
Seq C1 exon
AGTCAGCTATCGGACAGCCTATCGACATGGGGAGAAGACTATGTATAGGCGCAAGTCTCAGTGTTGTCCTGGATTTTATGAAAGCGGGGAAATGTGTGTCC
Seq A exon
CCCACTGTGCTGATAAATGTGTCCATGGTCGCTGTATTGCTCCAAACACCTGTCAGTGTGAGCCTGGCTGGGGAGGGACCAACTGCTCCAGTG
Seq C2 exon
CCTGCGATGGTGATCACTGGGGTCCCCACTGCACCAGCCGGTGCCAGTGCAAAAATGGGGCTCTGTGCAACCCCATCACCGGGGCTTGCCACTGTGCTGCGGGCTTCCGGGGCTGGCGCTGCGAGGACCGCTGTGAGCAGGGCACCTATGGTAACGACTGTCATCAGAGATGCCAGTGCCAGAATGGAGCCACCTGCGACCACGTCACGGGGGAATGCCGCTGCCCACCAGGATACACCGGAGCCTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF075468=EMI=PD(39.7=82.9)
A:
PF126612=hEGF=WD(100=40.6)
C2:
PF0005319=Laminin_EGF=WD(100=55.4),PF126612=hEGF=PU(84.6=13.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAAGCGGGGAAATGTGTGT
R:
TTACCATAGGTGCCCTGCTCA
Band lengths:
177-270
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)