HsaEX0038902 @ hg38
Exon Skipping
Gene
ENSG00000087995 | METTL2A
Description
methyltransferase like 2A [Source:HGNC Symbol;Acc:HGNC:25755]
Coordinates
chr17:62423867-62426654:+
Coord C1 exon
chr17:62423867-62424012
Coord A exon
chr17:62424219-62424310
Coord C2 exon
chr17:62426299-62426654
Length
92 bp
Sequences
Splice sites
3' ss Seq
TGCCCGTTTGATTTTCTCAGGGA
3' ss Score
8.56
5' ss Seq
AAGGTGCGC
5' ss Score
9.05
Exon sequences
Seq C1 exon
CGTTACGGAAAGTAAAGTGTTTCCGGCTCCGGTGTCATGGCCGGCTCCTACCCTGAAGGTGCACCTGCAGTCCTCGCCGATAAGAGGCAGCAGTTCGGAAGCCGGTTCCTGAGAGATCCGGCGCGCGTCTTCCACCACAATGCCTG
Seq A exon
GGACAATGTGGAGTGGTCGGAAGAGCAAGCCGCGGCGGCGGAGAGAAAAGTCCAGGAGAACAGTATCCAGCGGGTGTGCCAGGAGAAACAAG
Seq C2 exon
TTGATTATGAGATCAATGCCCACAAATACTGGAATGACTTCTACAAAATCCACGAAAATGGGTTTTTCAAGGATAGACATTGGCTTTTTACCGAATTCCCTGAGCTGGCACCTAGCCAAAATCAAAATCATTTGAAGGACTGGTTCTTGGAGAACAAGAGTGAAGTACCTGAATGTAGAAACAATGAGGATGGACCTGGTTTAATAATGGAAGAACAGCACAAGTGTTCTTCAAAGAGCCTTGAACATAAAACACAGACACTTCCTGTGGAGGAGAATGTAACTCAGAAAATTAGTGACCTGGAAATTTGTGCTGATGAGTTTCCTGGATCCTCAGCCACCTACCGAATACTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087995_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.053 A=0.406 C2=0.071
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF134891=Methyltransf_23=PU(17.6=28.6)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGATAAGAGGCAGCAGTTCGG
R:
TAGGTGCCAGCTCAGGGAATT
Band lengths:
183-275
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development