HsaEX0044856 @ hg19
Exon Skipping
Gene
ENSG00000110048 | OSBP
Description
oxysterol binding protein [Source:HGNC Symbol;Acc:8503]
Coordinates
chr11:59348924-59361728:-
Coord C1 exon
chr11:59361483-59361728
Coord A exon
chr11:59361077-59361197
Coord C2 exon
chr11:59348924-59349027
Length
121 bp
Sequences
Splice sites
3' ss Seq
TTGAACCTGATTTCTTCAAGGTG
3' ss Score
7.11
5' ss Seq
TCGGTAAGG
5' ss Score
10.48
Exon sequences
Seq C1 exon
GTAAACTTTAATGAGCCCTTGTCCATGCTTCAGCGCCTTACTGAAGATCTGGAATACCATGAGCTGTTAGACCGAGCTGCAAAATGTGAGAATTCTCTAGAACAGCTCTGTTATGTTGCAGCTTTCACCGTGTCCTCCTACTCCACTACTGTCTTCCGCACCAGTAAGCCATTCAACCCACTGCTTGGGGAGACCTTTGAGCTGGACCGATTAGAGGAGAATGGGTACCGATCCCTCTGTGAACAG
Seq A exon
GTGAGTCATCATCCCCCTGCTGCTGCGCACCATGCTGAGTCCAAAAATGGCTGGACATTGCGTCAGGAAATCAAAATCACCAGCAAGTTTCGAGGCAAATACCTCTCCATTATGCCCCTCG
Seq C2 exon
GTACCATTCATTGTATTTTCCATGCAACTGGGCACCACTACACTTGGAAGAAAGTTACCACAACTGTACACAACATTATTGTGGGCAAGTTGTGGATAGATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000110048_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.106 C2=0.000
Domain overlap (PFAM):
C1:
PF0123713=Oxysterol_BP=FE(21.5=100)
A:
PF0123713=Oxysterol_BP=FE(10.6=100)
C2:
PF0123713=Oxysterol_BP=FE(9.0=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATGCTTCAGCGCCTTACTGA
R:
GTGCCCAGTTGCATGGAAAAT
Band lengths:
258-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)