HsaEX0045419 @ hg19
Exon Skipping
Gene
ENSG00000100767 | PAPLN
Description
papilin, proteoglycan-like sulfated glycoprotein [Source:HGNC Symbol;Acc:19262]
Coordinates
chr14:73732078-73735431:+
Coord C1 exon
chr14:73732078-73732215
Coord A exon
chr14:73733431-73733539
Coord C2 exon
chr14:73735265-73735431
Length
109 bp
Sequences
Splice sites
3' ss Seq
TGACTTGTCCTTGTGCCCAGGGG
3' ss Score
8.39
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
Exon sequences
Seq C1 exon
GCTGCGTTTGGACCAGAACCAGCCCCGGGTGGTGGATGCCAGTCCAGGCCAGCGGATCCGGATGACCTGCCGTGCCGAAGGCTTCCCGCCCCCAGCCATCGAGTGGCAGAGAGATGGGCAGCCTGTCTCTTCTCCCAG
Seq A exon
GGGAGCTGACAATCTCAGGACTGCCCCCTACTGTGACAGTGCCAGAGGGTGATACGGCCAGGCTATTGTGTGTGGTAGCAGGAGAAAGTGTGAACATCAGGTGGTCCAG
Seq C2 exon
GAACGGGCTACCTGTGCAGGCTGATGGCCACCGTGTCCACCAGTCCCCAGATGGCACGCTGCTCATTTACAACTTGCGGGCCAGGGATGAGGGCTCCTACACGTGCAGTGCCTACCAGGGGAGCCAGGCAGTCAGCCGCAGCACCGAGGTGAAGGTGGTCTCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100767_MULTIEX1-2/3=C1-3
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.889 A=0.108 C2=0.228
Domain overlap (PFAM):
C1:
PF0767911=I-set=PU(50.0=89.4)
A:
PF0767911=I-set=PU(39.1=91.9)
C2:
PF0767911=I-set=PD(59.8=91.2)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCGTTTGGACCAGAACCAG
R:
TAGGCACTGCACGTGTAGGAG
Band lengths:
251-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)