HsaEX0046268 @ hg38
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:666531-670782:+
Coord C1 exon
chr4:666531-666614
Coord A exon
chr4:667856-668006
Coord C2 exon
chr4:670046-670782
Length
151 bp
Sequences
Splice sites
3' ss Seq
GACTTCTCGACTCCCCTCAGGAG
3' ss Score
6.79
5' ss Seq
AAGGTCTGG
5' ss Score
3.93
Exon sequences
Seq C1 exon
CCTATGATGGACCGGAACAAGGCGGCCGAGCTCCCCAAGCTGCAAGTGGGCTTCATCGACTTCGTGTGCACATTCGTGTACAAG
Seq A exon
GAGTTCTCTCGTTTCCACGAAGAGATCCTGCCCATGTTCGACCGACTGCAGAACAATAGGAAAGAGTGGAAGGCGCTGGCTGATGAGTATGAGGCCAAAGTGAAGGCTCTGGAGGAGAAGGAGGAGGAGGAGAGGGTGGCAGCCAAGAAAG
Seq C2 exon
TAGGCACAGAAATTTGCAATGGCGGCCCAGCACCCAAGTCTTCAACCTGCTGTATCCTGTGAGCACTGGTCCCATGGGGACCCTATGGCTCCCTCAATCTTCACCCACTAGGATTTGGGTTCTGCCTGTGGCTATTTGCTACAAGAGGTTAGGAAGCCCAAGAAAATGACTGAAGATCATTCTGGATATTTTAATTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCCGTGGCACGATCTCAGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCACCACCACACATGGCTAATTTTTGTATTTTCAGTACAGATGGGGTTTCACCATATTGGGCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCACCCGCCTCAGCTTCCTGAAGTGCTGGGATTACAGGCATGAGCCACCACGCCCAGCCTGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.031 C2=0.043
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(10.8=100)
A:
PF0023314=PDEase_I=PD(23.5=66.7)
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTATGATGGACCGGAACAAGGC
R:
GGGCTTCCTAACCTCTTGTAGC
Band lengths:
242-393
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development