HsaEX0046394 @ hg38
Exon Skipping
Gene
ENSG00000005882 | PDK2
Description
pyruvate dehydrogenase kinase 2 [Source:HGNC Symbol;Acc:HGNC:8810]
Coordinates
chr17:50097423-50106069:+
Coord C1 exon
chr17:50097423-50097564
Coord A exon
chr17:50105371-50105442
Coord C2 exon
chr17:50105885-50106069
Length
72 bp
Sequences
Splice sites
3' ss Seq
CCCCTCCCGCCCCCACACAGGTA
3' ss Score
9.62
5' ss Seq
CCAGTGAGT
5' ss Score
8.28
Exon sequences
Seq C1 exon
GATCCAGCAATGCCTGTGAGAAAACCTCCTTCACCTTCCTCAGGCAGGAGCTGCCTGTGCGCCTGGCCAACATCATGAAAGAGATCAACCTGCTTCCCGACCGAGTGCTGAGCACACCCTCCGTGCAGCTGGTGCAGAGCTG
Seq A exon
GTATGTCCAGAGCCTCCTGGACATCATGGAGTTCCTGGACAAGGATCCCGAGGACCATCGCACCCTGAGCCA
Seq C2 exon
GTTCACTGACGCCCTGGTCACCATCCGGAACCGGCACAACGACGTGGTGCCCACCATGGCACAAGGCGTGCTTGAGTACAAGGACACCTACGGCGATGACCCCGTCTCCAACCAGAACATCCAGTACTTCCTGGACCGCTTCTACCTCAGCCGCATCTCCATCCGCATGCTCATCAACCAGCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005882-'8-17,'8-16,16-17
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.021 C2=0.000
Domain overlap (PFAM):
C1:
PF104364=BCDHK_Adom3=PU(17.1=95.7)
A:
PF104364=BCDHK_Adom3=PU(15.3=93.8)
C2:
PF104364=BCDHK_Adom3=PD(52.0=96.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGATCAACCTGCTTCCCGAC
R:
GATGTTCTGGTTGGAGACGGG
Band lengths:
183-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development