HsaEX0047881 @ hg38
Exon Skipping
Gene
ENSG00000065243 | PKN2
Description
protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]
Coordinates
chr1:88824310-88833157:+
Coord C1 exon
chr1:88824310-88824386
Coord A exon
chr1:88828481-88828623
Coord C2 exon
chr1:88833077-88833157
Length
143 bp
Sequences
Splice sites
3' ss Seq
TTACATTTTATCTTTTCCAGGAA
3' ss Score
10.93
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
AGATTTGAAATTGGATAACTTATTGCTAGATACAGAGGGCTTTGTGAAAATTGCTGATTTTGGTCTTTGCAAAGAAG
Seq A exon
GAATGGGATATGGAGATAGAACAAGCACATTTTGTGGCACTCCTGAATTTCTTGCCCCAGAAGTATTAACAGAAACTTCTTATACAAGGGCTGTAGATTGGTGGGGCCTTGGCGTGCTTATATATGAAATGCTTGTTGGTGAG
Seq C2 exon
CTGTTAAGAAGAAATCCTGAACGGCGCCTTGGGGCTAGCGAGAAAGATGCAGAGGATGTAAAAAAGCACCCATTTTTCCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000065243_MULTIEX5-5/7=3-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.148
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.0=100)
A:
PF0006920=Pkinase=FE(18.1=100)
C2:
PF0006920=Pkinase=PD(9.6=92.6)
Main Skipping Isoform:
ENST00000370521fB22685
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTATTGCTAGATACAGAGGGCT
R:
CCGGAAAAATGGGTGCTTTTT
Band lengths:
141-284
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development