HsaEX0049467 @ hg38
Exon Skipping
Gene
ENSG00000118898 | PPL
Description
periplakin [Source:HGNC Symbol;Acc:HGNC:9273]
Coordinates
chr16:4897675-4899384:-
Coord C1 exon
chr16:4899223-4899384
Coord A exon
chr16:4899013-4899120
Coord C2 exon
chr16:4897675-4897770
Length
108 bp
Sequences
Splice sites
3' ss Seq
TCCACTGCCCCCCACTGCAGAAT
3' ss Score
9.34
5' ss Seq
GAGGTTCAT
5' ss Score
1.75
Exon sequences
Seq C1 exon
GCAGCATCACAGGCCCGGCAGCAGCACCTGAGTTCGCTGCAGGACTACATGCAGCGCTGCACCAATGAGCTGTACTGGCTGGACCAGCAGGCCAAGGGCCGCATGCAGTACGACTGGAGTGACCGCAACCTCGACTACCCCAGCCGCCGGCGCCAGTATGAG
Seq A exon
AATTTCATCAACCGGAACCTGGAGGCCAAAGAGGAGAGAATCAACAAACTGCACAGCGAGGGCGACCAGCTGCTGGCGGCCGAGCACCCCGGGAGGAACTCCATTGAG
Seq C2 exon
GCGCACATGGAGGCTGTGCACGCAGACTGGAAGGAGTACCTGAACCTGCTCATCTGCGAGGAGAGCCACCTCAAGTACATGGAGGACTACCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000118898_MULTIEX1-5/18=4-6
Average complexity
S
Mappability confidence:
88%=88=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.032 A=0.500 C2=0.031
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PU(41.3=79.6)
A:
PF0043516=Spectrin=FE(33.7=100)
C2:
PF0043516=Spectrin=PD(22.1=71.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCAGCAGCACCTGAGTTC
R:
AGTCCTCCATGTACTTGAGGTGG
Band lengths:
234-342
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development