HsaEX0051456 @ hg38
Exon Skipping
Gene
ENSG00000172053 | QARS
Description
glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]
Coordinates
chr3:49101355-49101899:-
Coord C1 exon
chr3:49101828-49101899
Coord A exon
chr3:49101620-49101705
Coord C2 exon
chr3:49101355-49101441
Length
86 bp
Sequences
Splice sites
3' ss Seq
GCTTATTCTGGTCCTGGCAGGTG
3' ss Score
8.62
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
Exon sequences
Seq C1 exon
GCGAGACTGCTGACCAGACCCTGTCTCTGATGGAGCAGCTCCGGGGGGAGGCCCTTAAGTTCCACAAGCCTG
Seq A exon
GTGAGAACTACAAGACCCCAGGCTATGTGGTCACTCCACACACCATGAATCTACTAAAGCAGCACCTGGAGATTACTGGTGGGCAG
Seq C2 exon
GTACGTACCCGGTTCCCGCCAGAACCCAATGGAATCCTGCATATTGGACATGCCAAAGCCATCAATTTCAACTTTGGCTATGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172053_MULTIEX1-7/13=6-8
Average complexity
S
Mappability confidence:
83%=83=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.247 A=0.053 C2=0.133
Domain overlap (PFAM):
C1:
PF0455710=tRNA_synt_1c_R2=FE(25.8=100)
A:
PF0455710=tRNA_synt_1c_R2=PD(22.6=72.4),PF0074916=tRNA-synt_1c=PU(7.1=20.7)
C2:
PF0074916=tRNA-synt_1c=FE(80.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGAGACTGCTGACCAGAC
R:
AGCCAAAGTTGAAATTGATGGCT
Band lengths:
151-237
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development