HsaEX0052378 @ hg38
Exon Skipping
Gene
ENSG00000170667 | RASA4B
Description
RAS p21 protein activator 4B [Source:HGNC Symbol;Acc:HGNC:35202]
Coordinates
chr7:102488463-102493285:-
Coord C1 exon
chr7:102493116-102493285
Coord A exon
chr7:102490986-102491123
Coord C2 exon
chr7:102488463-102488598
Length
138 bp
Sequences
Splice sites
3' ss Seq
CTCCTCCCTGCCTGCCCCAGAAA
3' ss Score
7.86
5' ss Seq
AAGGTGCGG
5' ss Score
8.17
Exon sequences
Seq C1 exon
AGCTGGACCTGCAGCGGACGCTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGACCAAGGGCAAGGGCCCCCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCCCAGCTCCAAG
Seq A exon
AAAAGCGCCCTCATCAAGTTAGCCAACATCCGGGCAGCGGAAAAGGTTGAGGAAAAGAGCTTTGGCGGCTCGCACGTCATGCAGGTCATCTACACGGACGACGCCGGCAGGCCCCAGACTGCCTACCTGCAGTGCAAG
Seq C2 exon
TGTGTGAATGAGCTTAACCAGTGGCTGTCTGCGCTGCGGAAGGTGAGCATCAACAACACCGGACTGCTGGGCTCCTACCACCCTGGCGTCTTCCGTGGGGACAAGTGGAGCTGCTGCCACCAAAAAGAGAAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000170667_MULTIEX1-1/3=C1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.048 A=0.000 C2=0.027
Domain overlap (PFAM):
C1:
PF0016924=PH=PU(40.6=75.4)
A:
PF0016924=PH=FE(42.5=100)
C2:
PF0016924=PH=PD(14.2=32.6),PF0077914=BTK=PU(68.8=47.8)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCACTCTTCATCCACAGGAC
R:
TCTTTTTGGTGGCAGCAGCTC
Band lengths:
246-384
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development