HsaEX0056666 @ hg19
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain, EGF-like 2 [Source:HGNC Symbol;Acc:30425]
Coordinates
chr11:9047249-9051592:-
Coord C1 exon
chr11:9051431-9051592
Coord A exon
chr11:9048911-9049108
Coord C2 exon
chr11:9047249-9047401
Length
198 bp
Sequences
Splice sites
3' ss Seq
CGGGGCATCTCCTTTTTCAGACA
3' ss Score
7.67
5' ss Seq
CCTGTGCGT
5' ss Score
4.27
Exon sequences
Seq C1 exon
TTCAATGTTCACCTGGACATTTCTACAACACCACCACTCACCGATGTATTCGTTGCCCAGTGGGAACATACCAGCCTGAATTTGGAAAAAATAATTGTGTTTCTTGCCCAGGAAATACTACGACTGACTTTGATGGCTCCACAAACATAACCCAGTGTAAAA
Seq A exon
ACAGAAGATGTGGAGGGGAGCTGGGAGATTTCACTGGGTACATTGAATCCCCAAACTACCCAGGCAATTACCCAGCCAACACCGAGTGTACGTGGACCATCAACCCACCCCCCAAGCGCCGCATCCTGATCGTGGTCCCTGAGATCTTCCTGCCCATAGAGGACGACTGTGGGGACTATCTGGTGATGCGGAAAACCT
Seq C2 exon
CTTCATCCAATTCTGTGACAACATATGAAACCTGCCAGACCTACGAACGCCCCATCGCCTTCACCTCCAGGTCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGGAACAGCGCTAGAGGGTTCCAGGTCCCATACGTGACATATGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.015 C2=0.006
Domain overlap (PFAM):
C1:
PF076998=GCC2_GCC3=WD(100=87.3)
A:
PF0043115=CUB=PU(57.3=94.0)
C2:
PF0043115=CUB=PD(41.8=88.5)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCGATGTATTCGTTGCCCA
R:
TAGCGCTGTTCCCTTCATTGG
Band lengths:
244-442
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)